Gene detail

AMR89_RS00145

Histidine kinase, Classic

Clostridioides difficile · GCF_002891605

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002891605#AMR89_RS00145Stable P2CS identifier used across views.
GenomeGCF_002891605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2181824Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_102814246.1 · MIST4 AMR89_RS00145RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage337 / 429 aa (78.6%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
HAMP: 9-74 aa (66 aa)1PAS_9: 96-195 aa (100 aa)2HisKA: 202-268 aa (67 aa)3HATPase_c: 319-422 aa (104 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
9-74 aa · 66 aa · 15.4% of protein
Raw tokenHAMP:9:0.000000449:74:68:69
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw tokenPAS_9:96:0.00000129:195:103:102
3 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw tokenHisKA:202:3.04e-18:268:67:64
4 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw tokenHATPase_c:319:3.98e-30:422:104:109
  • Raw architecture: HAMP:9:0.000000449:74:68:69#PAS_9:96:0.00000129:195:103:102#HisKA:202:3.04e-18:268:67:64#HATPase_c:319:3.98e-30:422:104:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002891605::NZ_LJCK01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span31230-33240Genomic interval covered by the local TCS group.
Context group IDGCF_002891605::NZ_LJCK01000001.1::G00001
Context members
AMR89_RS00140AMR89_RS00145
Partner locus tags
AMR89_RS00140AMR89_RS00145
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_102814246.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAMR89_RS00145Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_LJCK01000001.1Sequence record reported by the local genomic context database.
Genomic interval31 951-33 240 nt1 290 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span31 230-33 240 ntGCF_002891605::NZ_LJCK01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002891605::NZ_LJCK01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LJCK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span31 230-33 240 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
31 230 nt33 240 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AMR89_RS00140GCF_002891605#AMR89_RS00140
RROmpR

31 230-31 922 nt · Forward (+)

RefSeq WP_003416112.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2181824Run 6 · HK · 1 sequences
Representative sequenceGCF_002891605#AMR89_RS00145The current gene is the representative for this cluster.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2181824

Simplified PFAM architecture for HKOC_2181824

PFAM domain coverage: 323 / 429 aa (75.3%)

1 aa429 aa
HAMP: 31-74 aaHAMPPAS: 87-193 aaPASHisKA: 202-267 aaHisKAHATPase_c: 317-422 aaHATPase_c
HAMPPASHisKAHATPase_c
  • Simplified architecture: HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: HAMP[31-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
  • Domain count: 4
  • Matched identifier: HKOC_2181824
  • Positioned domains: HAMP 31-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891605#AMR89_RS00145

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002891605
AssemblyASM289160v1 · Scaffoldhaploid
Genome composition4 144 242 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key