Gene detail

CWR57_RS09570

Histidine kinase, Classic

Clostridioides difficile · GCF_002812585

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002812585#CWR57_RS09570Stable P2CS identifier used across views.
GenomeGCF_002812585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747612Run 6 · 337 sequences · id 100% · cov 80%
External referencesWP_009889918.1 · A0A0H3N7T9 · MIST4 CWR57_RS09570RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 467 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HisKA: 245-313 aa (69 aa)1HATPase_c: 360-466 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-313 aa · 69 aa · 14.8% of protein
Raw tokenHisKA:245:0.000000000000205:313:69:64
2 HATPase_c#2
360-466 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:360:1.05e-27:466:108:109
  • Raw architecture: HisKA:245:0.000000000000205:313:69:64#HATPase_c:360:1.05e-27:466:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_002812585::NZ_CP025044.1::G00033
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2002801-2004204Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCWR57_09570RefSeq proteinWP_009889918.1
Context group IDGCF_002812585::NZ_CP025044.1::G00033
Context members
CWR57_RS09570
Partner locus tags
CWR57_RS09570
Partner old locus tags
CWR57_09570
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889918.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N7T9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N7T9_CLODCDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
GO terms
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCWR57_RS09570Primary locus identifier stored in the genes table.
Old locus tagCWR57_09570Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP025044.1Sequence record reported by the local genomic context database.
Genomic interval2 002 801-2 004 204 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 002 801-2 004 204 ntGCF_002812585::NZ_CP025044.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002812585::NZ_CP025044.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP025044.1All displayed genes belong to this local TCS context.
Neighborhood span2 002 801-2 004 204 nt1 404 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 002 801 nt2 004 204 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

CWR57_RS09570GCF_002812585#CWR57_RS09570
HKClassicCurrent focus

2 002 801-2 004 204 nt · Reverse (-)

Old locus CWR57_09570RefSeq WP_009889918.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747612Run 6 · HK · 337 sequences
Representative sequenceGCF_000003215#QAC_RS0209850Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747612

Simplified PFAM architecture for HKOC_1747612

PFAM domain coverage: 167 / 467 aa (35.8%)

1 aa467 aa
HisKA: 245-306 aaHisKAHATPase_c: 362-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-306] | HATPase_c[362-466]
  • Domain count: 2
  • Matched identifier: HKOC_1747612
  • Positioned domains: HisKA 245-306 ; HATPase_c 362-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209850

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 337 total members. Page 1 / 7.

GCF_000003215#QAC_RS0209850 (representative)
QAC_RS0209850 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000027105#CDR20291_RS10270
CDR20291_RS10270 · HK · Classic
RefSeq: WP_021407249.1
GCF_000085225#CD196_RS09960
CD196_RS09960 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000154645#UAA_RS0211725
UAA_RS0211725 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000154665#QAD_RS0210025
QAD_RS0210025 · HK · Classic
RefSeq: WP_021407249.1
GCF_000154685#AEC_RS0211335
AEC_RS0211335 · HK · Classic
RefSeq: WP_021407249.1
GCF_000155045#EAA_RS0209765
EAA_RS0209765 · HK · Classic
RefSeq: WP_021407249.1
GCF_000210455#CD7855_RS09780
CD7855_RS09780 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000211235#CDBI1_RS09870
CDBI1_RS09870 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000450765#QO5_RS10515
QO5_RS10515 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000451065#QSC_RS09610
QSC_RS09610 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000451785#QSO_RS08605
QSO_RS08605 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000451885#QU5_RS09675
QU5_RS09675 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_000826625#BN2378_RS18405
BN2378_RS18405 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_001484885#CD26A54R_RS09785
CD26A54R_RS09785 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_001484895#CD26A54S_RS09895
CD26A54S_RS09895 · HK · Classic
RefSeq: WP_021407249.1
GCF_001857645#HMPREF3082_RS16730
HMPREF3082_RS16730 · HK · Classic
RefSeq: WP_021407249.1
GCF_001971835#BER28_RS10215
BER28_RS10215 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_001972015#BER29_RS10160
BER29_RS10160 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002303165#BGV24_RS16345
BGV24_RS16345 · HK · Classic
RefSeq: WP_021407249.1
GCF_002335485#NCKUH21_RS09625
NCKUH21_RS09625 · HK · Classic
RefSeq: WP_021407249.1
GCF_002812585#CWR57_RS09570
CWR57_RS09570 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002945415#C3W74_RS10245
C3W74_RS10245 · HK · Classic
RefSeq: WP_021407249.1
GCF_002945515#C3L34_RS10730
C3L34_RS10730 · HK · Classic
RefSeq: WP_021407249.1
GCF_002945665#C3347_RS10245
C3347_RS10245 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002945755#C3348_RS10250
C3348_RS10250 · HK · Classic
RefSeq: WP_021407249.1
GCF_002945855#C3350_RS10260
C3350_RS10260 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002945945#C3349_RS10250
C3349_RS10250 · HK · Classic
RefSeq: WP_021407249.1
GCF_002946035#C3351_RS10255
C3351_RS10255 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002946135#C3352_RS10255
C3352_RS10255 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002946195#C3353_RS10245
C3353_RS10245 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_002954285#AMR92_RS14280
AMR92_RS14280 · HK · Classic
RefSeq: WP_021407249.1
GCF_002954305#AMR91_RS02085
AMR91_RS02085 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003313545#CDIF27638_RS10250
CDIF27638_RS10250 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003313585#CDIF27640_RS10240
CDIF27640_RS10240 · HK · Classic
RefSeq: WP_021407249.1
GCF_003482035#CDIF28196_RS10255
CDIF28196_RS10255 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003597795#DA426_RS09665
DA426_RS09665 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003597815#DA430_RS10245
DA430_RS10245 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003597835#DA432_RS10200
DA432_RS10200 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003597895#DA422_RS10010
DA422_RS10010 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003597915#DA436_RS10195
DA436_RS10195 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003625415#C0215_RS00200
C0215_RS00200 · HK · Classic
RefSeq: WP_021407249.1
GCF_003625425#C0983_RS09370
C0983_RS09370 · HK · Classic
RefSeq: WP_021407249.1
GCF_003625435#C0984_RS15995
C0984_RS15995 · HK · Classic
RefSeq: WP_021407249.1
GCF_003862685#EGM06_RS02545
EGM06_RS02545 · HK · Classic
RefSeq: WP_021407249.1
GCF_003863035#EGL82_RS01985
EGL82_RS01985 · HK · Classic
RefSeq: WP_021407249.1
GCF_003863055#EGM11_RS01765
EGM11_RS01765 · HK · Classic
RefSeq: WP_021407249.1
GCF_003863075#EGL79_RS00175
EGL79_RS00175 · HK · Classic
RefSeq: WP_009889918.1
UniProt: A0A0H3N7T9
GCF_003863145#EGM12_RS01760
EGM12_RS01760 · HK · Classic
RefSeq: WP_021407249.1
GCF_003863195#EGM01_RS08100
EGM01_RS08100 · HK · Classic
RefSeq: WP_021407249.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002812585
AssemblyASM281258v1 · Complete Genomehaploid
Genome composition4 190 038 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key