Gene detail

CON35_RS03440

Histidine kinase, Classic

Bacillus cereus · GCF_002553255

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002553255#CON35_RS03440Stable P2CS identifier used across views.
GenomeGCF_002553255Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1115796Run 6 · 53 sequences · id 100% · cov 80% · representative
External referencesWP_098938307.1 · MIST4 CON35_RS03440RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 589 aa (79.8%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
sCache_like: 35-149 aa (115 aa)1HAMP: 165-234 aa (70 aa)2PAS: 245-351 aa (107 aa)3HisKA: 360-427 aa (68 aa)4HATPase_c: 472-581 aa (110 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-149 aa · 115 aa · 19.5% of protein
Raw tokensCache_like:35:9.69e-30:149:117:114
2 HAMP#2
165-234 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:165:0.0000000000094:234:70:69
3 PAS#3
245-351 aa · 107 aa · 18.2% of protein
Raw tokenPAS:245:0.0000000000000371:351:112:113
4 HisKA#4
360-427 aa · 68 aa · 11.5% of protein
Raw tokenHisKA:360:1.72e-21:427:68:64
5 HATPase_c#5
472-581 aa · 110 aa · 18.7% of protein
Raw tokenHATPase_c:472:7.5e-36:581:110:109
  • Raw architecture: sCache_like:35:9.69e-30:149:117:114#HAMP:165:0.0000000000094:234:70:69#PAS:245:0.0000000000000371:351:112:113#HisKA:360:1.72e-21:427:68:64#HATPase_c:472:7.5e-36:581:110:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002553255::NZ_NVMR01000014.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span58231-60712Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCON35_03440RefSeq proteinWP_098938307.1
Context group IDGCF_002553255::NZ_NVMR01000014.1::G00009
Context members
CON35_RS03435CON35_RS03440
Partner locus tags
CON35_RS03435CON35_RS03440
Partner old locus tags
CON35_03435CON35_03440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_098938307.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCON35_RS03440Primary locus identifier stored in the genes table.
Old locus tagCON35_03440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NVMR01000014.1Sequence record reported by the local genomic context database.
Genomic interval58 943-60 712 nt1 770 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span58 231-60 712 ntGCF_002553255::NZ_NVMR01000014.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002553255::NZ_NVMR01000014.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NVMR01000014.1All displayed genes belong to this local TCS context.
Neighborhood span58 231-60 712 nt2 482 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
58 231 nt60 712 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CON35_RS03435GCF_002553255#CON35_RS03435
RROmpR

58 231-58 950 nt · Forward (+)

Old locus CON35_03435RefSeq WP_001065220.1
CON35_RS03440GCF_002553255#CON35_RS03440
HKClassicCurrent focus

58 943-60 712 nt · Forward (+)

Old locus CON35_03440RefSeq WP_098938307.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1115796Run 6 · HK · 53 sequences
Representative sequenceGCF_002553255#CON35_RS03440The current gene is the representative for this cluster.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1115796

Simplified PFAM architecture for HKOC_1115796

PFAM domain coverage: 449 / 589 aa (76.2%)

1 aa589 aa
sCache_like: 33-149 aasCache_likeHAMP: 188-234 aaHAMPPAS: 245-351 aaPASHisKA: 360-426 aaHisKAHATPase_c: 472-582 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-149] | HAMP[188-234] | PAS[245-351] | HisKA[360-426] | HATPase_c[472-582]
  • Domain count: 5
  • Matched identifier: HKOC_1115796
  • Positioned domains: sCache_like 33-149 ; HAMP 188-234 ; PAS 245-351 ; HisKA 360-426 ; HATPase_c 472-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_002553255#CON35_RS03440

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 396 · GCF_002553255
AssemblyASM255325v1 · Scaffoldhaploid
Genome composition5 910 033 bp · 35,0% GCBacillus cereus
Signal transduction countsGenes 103 · HK 55 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key