Gene detail

AWP82_RS02260

Histidine kinase, Classic

Escherichia coli · GCF_001911225

ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_001911225#AWP82_RS02260Stable P2CS identifier used across views.
GenomeGCF_001911225Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1646917Run 6 · 6725 sequences · id 100% · cov 80% · representative
External referencesWP_074514251.1 · MIST4 AWP82_RS02260RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 477 aa (51.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa477 aa
HAMP: 175-243 aa (69 aa)1HisKA: 249-316 aa (68 aa)2HATPase_c: 362-469 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
175-243 aa · 69 aa · 14.5% of protein
Raw tokenHAMP:175:0.000000352:243:69:69
2 HisKA#2
249-316 aa · 68 aa · 14.3% of protein
Raw tokenHisKA:249:0.0000000000000134:316:68:64
3 HATPase_c#3
362-469 aa · 108 aa · 22.6% of protein
Raw tokenHATPase_c:362:1.32e-23:469:108:109
  • Raw architecture: HAMP:175:0.000000352:243:69:69#HisKA:249:0.0000000000000134:316:68:64#HATPase_c:362:1.32e-23:469:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_001911225::NZ_LRLL01000044.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span27495-28928Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWP82_02260RefSeq proteinWP_074514251.1
Context group IDGCF_001911225::NZ_LRLL01000044.1::G00004
Context members
AWP82_RS02260
Partner locus tags
AWP82_RS02260
Partner old locus tags
AWP82_02260
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074514251.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAWP82_RS02260Primary locus identifier stored in the genes table.
Old locus tagAWP82_02260Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LRLL01000044.1Sequence record reported by the local genomic context database.
Genomic interval27 495-28 928 nt1 434 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 495-28 928 ntGCF_001911225::NZ_LRLL01000044.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001911225::NZ_LRLL01000044.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LRLL01000044.1All displayed genes belong to this local TCS context.
Neighborhood span27 495-28 928 nt1 434 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 495 nt28 928 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

AWP82_RS02260GCF_001911225#AWP82_RS02260
HKClassicCurrent focus

27 495-28 928 nt · Reverse (-)

Old locus AWP82_02260RefSeq WP_074514251.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1646917Run 6 · HK · 6725 sequences
Representative sequenceGCF_001911225#AWP82_RS02260The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1646917

Simplified PFAM architecture for HKOC_1646917

PFAM domain coverage: 229 / 477 aa (48.0%)

1 aa477 aa
HAMP: 192-244 aaHAMPHisKA: 250-316 aaHisKAHATPase_c: 362-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[192-244] | HisKA[250-316] | HATPase_c[362-470]
  • Domain count: 3
  • Matched identifier: HKOC_1646917
  • Positioned domains: HAMP 192-244 ; HisKA 250-316 ; HATPase_c 362-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_001911225#AWP82_RS02260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_001911225
AssemblyASM191122v1 · Contighaploid
Genome composition4 922 465 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key