Gene detail

BW28_RS10740

Histidine kinase, Classic

Clostridioides difficile · GCF_001757605

ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757605#BW28_RS10740Stable P2CS identifier used across views.
GenomeGCF_001757605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2880556Run 6 · 256 sequences · id 100% · cov 80%
External referencesWP_003427141.1 · A0A9P3U2X2 · MIST4 BW28_RS10740RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa307 aa
HisKA: 89-151 aa (63 aa)1HATPase_c: 199-306 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw tokenHisKA:89:0.0000000568:151:63:64
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw tokenHATPase_c:199:1.12e-29:306:108:109
  • Raw architecture: HisKA:89:0.0000000568:151:63:64#HATPase_c:199:1.12e-29:306:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757605::NZ_JFOF01000041.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4412-6038Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW28_09390RefSeq proteinWP_003427141.1
Context group IDGCF_001757605::NZ_JFOF01000041.1::G00028
Context members
BW28_RS10740BW28_RS10745
Partner locus tags
BW28_RS10740BW28_RS10745
Partner old locus tags
BW28_09390BW28_09395
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003427141.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3U2X2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3U2X2_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW28_RS10740Primary locus identifier stored in the genes table.
Old locus tagBW28_09390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOF01000041.1Sequence record reported by the local genomic context database.
Genomic interval4 412-5 335 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 412-6 038 ntGCF_001757605::NZ_JFOF01000041.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757605::NZ_JFOF01000041.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOF01000041.1All displayed genes belong to this local TCS context.
Neighborhood span4 412-6 038 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 412 nt6 038 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BW28_RS10740GCF_001757605#BW28_RS10740
HKClassicCurrent focus

4 412-5 335 nt · Reverse (-)

Old locus BW28_09390RefSeq WP_003427141.1
BW28_RS10745GCF_001757605#BW28_RS10745
RROmpR

5 337-6 038 nt · Reverse (-)

Old locus BW28_09395RefSeq WP_003427144.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2880556Run 6 · HK · 256 sequences
Representative sequenceGCF_000210395#CDM68_RS01805Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2880556

Simplified PFAM architecture for HKOC_2880556

PFAM domain coverage: 172 / 307 aa (56.0%)

1 aa307 aa
HisKA: 88-151 aaHisKAHATPase_c: 199-306 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-151] | HATPase_c[199-306]
  • Domain count: 2
  • Matched identifier: HKOC_2880556
  • Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS01805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757605
AssemblyASM175760v1 · Contighaploid
Genome composition4 317 574 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key