Gene detail

BW28_RS00320

Histidine kinase, Classic

Clostridioides difficile · GCF_001757605

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757605#BW28_RS00320Stable P2CS identifier used across views.
GenomeGCF_001757605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2558520Run 6 · 17 sequences · id 100% · cov 80% · representative
External referencesWP_070112038.1 · MIST4 BW28_RS00320RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000572:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.00000006:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.94e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000572:152:70:69#HisKA:164:0.00000006:217:54:64#HATPase_c:278:1.94e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757605::NZ_JFOF01000007.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span34151-35973Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW28_17790RefSeq proteinWP_070112038.1
Context group IDGCF_001757605::NZ_JFOF01000007.1::G00045
Context members
BW28_RS00315BW28_RS00320
Partner locus tags
BW28_RS00315BW28_RS00320
Partner old locus tags
BW28_17785BW28_17790
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070112038.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW28_RS00320Primary locus identifier stored in the genes table.
Old locus tagBW28_17790Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOF01000007.1Sequence record reported by the local genomic context database.
Genomic interval34 813-35 973 nt1 161 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span34 151-35 973 ntGCF_001757605::NZ_JFOF01000007.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757605::NZ_JFOF01000007.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOF01000007.1All displayed genes belong to this local TCS context.
Neighborhood span34 151-35 973 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 151 nt35 973 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BW28_RS00315GCF_001757605#BW28_RS00315
RROmpR

34 151-34 825 nt · Forward (+)

Old locus BW28_17785RefSeq WP_022616687.1
BW28_RS00320GCF_001757605#BW28_RS00320
HKClassicCurrent focus

34 813-35 973 nt · Forward (+)

Old locus BW28_17790RefSeq WP_070112038.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2558520Run 6 · HK · 17 sequences
Representative sequenceGCF_001757605#BW28_RS00320The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2558520

Simplified PFAM architecture for HKOC_2558520

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2558520
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_001757605#BW28_RS00320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757605
AssemblyASM175760v1 · Contighaploid
Genome composition4 317 574 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key