Gene detail

BW25_RS13900

Histidine kinase, Classic

Clostridioides difficile · GCF_001757585

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757585#BW25_RS13900Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2073191Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_330388625.1 · MIST4 BW25_RS13900RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage349 / 440 aa (79.3%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
sCache_like: 15-112 aa (98 aa)1HAMP: 127-204 aa (78 aa)2HisKA: 216-281 aa (66 aa)3HATPase_c: 331-437 aa (107 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
15-112 aa · 98 aa · 22.3% of protein
Raw tokensCache_like:15:0.0000278:112:115:114
2 HAMP#2
127-204 aa · 78 aa · 17.7% of protein
Raw tokenHAMP:127:0.00000000694:204:78:69
3 HisKA#3
216-281 aa · 66 aa · 15.0% of protein
Raw tokenHisKA:216:0.00000000143:281:66:64
4 HATPase_c#4
331-437 aa · 107 aa · 24.3% of protein
Raw tokenHATPase_c:331:1.65e-26:437:107:109
  • Raw architecture: sCache_like:15:0.0000278:112:115:114#HAMP:127:0.00000000694:204:78:69#HisKA:216:0.00000000143:281:66:64#HATPase_c:331:1.65e-26:437:107:109
  • Domain description: 1 sCache_like,1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001757585::NZ_JFOH01000047.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span78335-80470Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_13280RefSeq proteinWP_330388625.1
Context group IDGCF_001757585::NZ_JFOH01000047.1::G00033
Context members
BW25_RS13895BW25_RS13900
Partner locus tags
BW25_RS13895BW25_RS13900
Partner old locus tags
BW25_13275BW25_13280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330388625.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBW25_RS13900Primary locus identifier stored in the genes table.
Old locus tagBW25_13280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000047.1Sequence record reported by the local genomic context database.
Genomic interval79 148-80 470 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span78 335-80 470 ntGCF_001757585::NZ_JFOH01000047.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001757585::NZ_JFOH01000047.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000047.1All displayed genes belong to this local TCS context.
Neighborhood span78 335-80 470 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
78 335 nt80 470 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BW25_RS13895GCF_001757585#BW25_RS13895
RROmpR

78 335-79 027 nt · Forward (+)

Old locus BW25_13275RefSeq WP_003426338.1
BW25_RS13900GCF_001757585#BW25_RS13900
HKClassicCurrent focus

79 148-80 470 nt · Forward (+)

Old locus BW25_13280RefSeq WP_330388625.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2073191Run 6 · HK · 2 sequences
Representative sequenceGCF_001757585#BW25_RS13900The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2073191

Simplified PFAM architecture for HKOC_2073191

PFAM domain coverage: 223 / 440 aa (50.7%)

1 aa440 aa
HAMP: 154-204 aaHAMPHisKA: 217-281 aaHisKAHATPase_c: 331-437 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
  • Domain count: 3
  • Matched identifier: HKOC_2073191
  • Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_001757585#BW25_RS13900

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key