1 PAS#1
521-632 aa · 112 aa · 12.3% of protein
Raw token
PAS:521:0.0000423:632:114:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BW25_RS01110
Histidine kinase, Classic
Clostridioides difficile · GCF_001757585
ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_001757585#BW25_RS01110Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage295 / 912 aa (32.3%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw token
HisKA:655:0.00000000000000811:726:72:643 HATPase_c#3
773-883 aa · 111 aa · 12.2% of protein
Raw token
HATPase_c:773:3.91e-31:883:111:109- Raw architecture: PAS:521:0.0000423:632:114:113#HisKA:655:0.00000000000000811:726:72:64#HATPase_c:773:3.91e-31:883:111:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_001757585::NZ_JFOH01000001.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span228177-230915Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_01115RefSeq proteinWP_070112530.1
Context group ID
GCF_001757585::NZ_JFOH01000001.1::G00002Context members
BW25_RS01110
Partner locus tags
BW25_RS01110
Partner old locus tags
BW25_01115
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_070112530.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBW25_RS01110Primary locus identifier stored in the genes table.
Old locus tagBW25_01115Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000001.1Sequence record reported by the local genomic context database.
Genomic interval228 177-230 915 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span228 177-230 915 ntGCF_001757585::NZ_JFOH01000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001757585::NZ_JFOH01000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span228 177-230 915 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
228 177 nt230 915 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
BW25_RS01110GCF_001757585#BW25_RS01110
HKClassicCurrent focus
228 177-230 915 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001757585#BW25_RS01110The current gene is the representative for this cluster.
PFAM architecturePAS_8 + PAS_9 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0388013
Simplified PFAM architecture for HKOC_0388013
PFAM domain coverage: 340 / 912 aa (37.3%)
1 aa912 aa
PAS_8PAS_9HisKAHATPase_c
- Simplified architecture: PAS_8 + PAS_9 + HisKA + HATPase_c
- Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-726] | HATPase_c[773-883]
- Domain count: 4
- Matched identifier: HKOC_0388013
- Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-726 ; HATPase_c 773-883
Cluster members and taxonomy
Representative gene: GCF_001757585#BW25_RS01110
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key