1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.0000000000000139:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BW25_RS00165
Histidine kinase, Classic
Clostridioides difficile · GCF_001757585
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001757585#BW25_RS00165Stable P2CS identifier used across views.
GenomeGCF_001757585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.000000158:513:90:109- Raw architecture: HisKA:309:0.0000000000000139:375:67:64#HATPase_c:428:0.000000158:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001757585::NZ_JFOH01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24093-26370Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBW25_00170RefSeq proteinWP_003430695.1
Context group ID
GCF_001757585::NZ_JFOH01000001.1::G00001Context members
BW25_RS00160BW25_RS00165
Partner locus tags
BW25_RS00160BW25_RS00165
Partner old locus tags
BW25_00165BW25_00170
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003430695.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YPW6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YPW6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBW25_RS00165Primary locus identifier stored in the genes table.
Old locus tagBW25_00170Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JFOH01000001.1Sequence record reported by the local genomic context database.
Genomic interval24 778-26 370 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span24 093-26 370 ntGCF_001757585::NZ_JFOH01000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001757585::NZ_JFOH01000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JFOH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span24 093-26 370 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 093 nt26 370 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BW25_RS00160GCF_001757585#BW25_RS00160
RROmpR
24 093-24 809 nt · Forward (+)
BW25_RS00165GCF_001757585#BW25_RS00165
HKClassicCurrent focus
24 778-26 370 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS11885Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1355562
Simplified PFAM architecture for HKOC_1355562
PFAM domain coverage: 188 / 530 aa (35.5%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-507]
- Domain count: 3
- Matched identifier: HKOC_1355562
- Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-507
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS11885
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_001757585
AssemblyASM175758v1 · Contighaploid
Genome composition4 181 809 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key