Gene detail

ARA40_RS04120

Histidine kinase, Classic

[Ruminococcus] torques · GCF_001405235

ClassHKTypeClassicLength606 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001405235#ARA40_RS04120Stable P2CS identifier used across views.
GenomeGCF_001405235Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1023694Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_055146026.1 · A0A174Y6E8 · MIST4 ARA40_RS04120RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length606 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage370 / 606 aa (61.1%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa606 aa
dCache_1: 187-299 aa (113 aa)1HAMP: 316-385 aa (70 aa)2His_kinase: 400-479 aa (80 aa)3HATPase_c: 496-602 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
187-299 aa · 113 aa · 18.6% of protein
Raw tokendCache_1:187:0.00000634:299:116:195
2 HAMP#2
316-385 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:316:0.0000000000308:385:73:69
3 His_kinase#3
400-479 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:400:1.51e-30:479:80:80
4 HATPase_c#4
496-602 aa · 107 aa · 17.7% of protein
Raw tokenHATPase_c:496:0.0000000000108:602:109:109
  • Raw architecture: dCache_1:187:0.00000634:299:116:195#HAMP:316:0.0000000000308:385:73:69#His_kinase:400:1.51e-30:479:80:80#HATPase_c:496:0.0000000000108:602:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001405235::NZ_CZBS01000003.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span59679-63068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852424_00840RefSeq proteinWP_055146026.1
Context group IDGCF_001405235::NZ_CZBS01000003.1::G00009
Context members
ARA40_RS04115ARA40_RS04120
Partner locus tags
ARA40_RS04115ARA40_RS04120
Partner old locus tags
ERS852424_00839ERS852424_00840
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055146026.1Primary protein accession used for annex mappings.
UniProt accessionA0A174Y6E8Primary UniProt accession resolved in the annex database.
UniProt IDA0A174Y6E8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA40_RS04120Primary locus identifier stored in the genes table.
Old locus tagERS852424_00840Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CZBS01000003.1Sequence record reported by the local genomic context database.
Genomic interval61 248-63 068 nt1 821 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span59 679-63 068 ntGCF_001405235::NZ_CZBS01000003.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001405235::NZ_CZBS01000003.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CZBS01000003.1All displayed genes belong to this local TCS context.
Neighborhood span59 679-63 068 nt3 390 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
59 679 nt63 068 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA40_RS04115GCF_001405235#ARA40_RS04115
RRunclassified

59 679-61 229 nt · Forward (+)

Old locus ERS852424_00839RefSeq WP_055146023.1
ARA40_RS04120GCF_001405235#ARA40_RS04120
HKClassicCurrent focus

61 248-63 068 nt · Forward (+)

Old locus ERS852424_00840RefSeq WP_055146026.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1023694Run 6 · HK · 4 sequences
Representative sequenceGCF_001405235#ARA40_RS04120The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1023694

Simplified PFAM architecture for HKOC_1023694

PFAM domain coverage: 184 / 606 aa (30.4%)

1 aa606 aa
His_kinase: 400-477 aaHis_kinaseHATPase_c: 497-602 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[400-477] | HATPase_c[497-602]
  • Domain count: 2
  • Matched identifier: HKOC_1023694
  • Positioned domains: His_kinase 400-477 ; HATPase_c 497-602
Cluster members and taxonomy
Visualization

Representative gene: GCF_001405235#ARA40_RS04120

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 039 · GCF_001405235
Assembly13414_6#51 · Scaffoldhaploid
Genome composition2 756 866 bp · 41,0% GC[Ruminococcus] torques
Signal transduction countsGenes 54 · HK 27 · RR 26CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key