Gene detail

ARA42_RS09170

Histidine kinase, Classic

Lachnospira eligens · GCF_001404435

ClassHKTypeClassicLength585 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001404435#ARA42_RS09170Stable P2CS identifier used across views.
GenomeGCF_001404435Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnospira
Selected clusterHKOC_1136754Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_055215876.1 · A0A174Z579 · MIST4 ARA42_RS09170RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length585 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage259 / 585 aa (44.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa585 aa
HAMP: 293-362 aa (70 aa)1His_kinase: 377-456 aa (80 aa)2HATPase_c: 472-580 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
293-362 aa · 70 aa · 12.0% of protein
Raw tokenHAMP:293:0.00000000000000132:362:70:69
2 His_kinase#2
377-456 aa · 80 aa · 13.7% of protein
Raw tokenHis_kinase:377:1.78e-30:456:80:80
3 HATPase_c#3
472-580 aa · 109 aa · 18.6% of protein
Raw tokenHATPase_c:472:0.000000000000453:580:118:109
  • Raw architecture: HAMP:293:0.00000000000000132:362:70:69#His_kinase:377:1.78e-30:456:80:80#HATPase_c:472:0.000000000000453:580:118:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001404435::NZ_CZBU01000004.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span146980-150278Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852490_01899RefSeq proteinWP_055215876.1
Context group IDGCF_001404435::NZ_CZBU01000004.1::G00026
Context members
ARA42_RS09165ARA42_RS09170
Partner locus tags
ARA42_RS09165ARA42_RS09170
Partner old locus tags
ERS852490_01898ERS852490_01899
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055215876.1Primary protein accession used for annex mappings.
UniProt accessionA0A174Z579Primary UniProt accession resolved in the annex database.
UniProt IDA0A174Z579_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA42_RS09170Primary locus identifier stored in the genes table.
Old locus tagERS852490_01899Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CZBU01000004.1Sequence record reported by the local genomic context database.
Genomic interval148 521-150 278 nt1 758 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span146 980-150 278 ntGCF_001404435::NZ_CZBU01000004.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001404435::NZ_CZBU01000004.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CZBU01000004.1All displayed genes belong to this local TCS context.
Neighborhood span146 980-150 278 nt3 299 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
146 980 nt150 278 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA42_RS09165GCF_001404435#ARA42_RS09165
RRunclassified

146 980-148 524 nt · Forward (+)

Old locus ERS852490_01898RefSeq WP_055215875.1
ARA42_RS09170GCF_001404435#ARA42_RS09170
HKClassicCurrent focus

148 521-150 278 nt · Forward (+)

Old locus ERS852490_01899RefSeq WP_055215876.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1136754Run 6 · HK · 2 sequences
Representative sequenceGCF_001404435#ARA42_RS09170The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1136754

Simplified PFAM architecture for HKOC_1136754

PFAM domain coverage: 237 / 585 aa (40.5%)

1 aa585 aa
HAMP: 311-361 aaHAMPHis_kinase: 378-455 aaHis_kinaseHATPase_c: 472-579 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[311-361] | His_kinase[378-455] | HATPase_c[472-579]
  • Domain count: 3
  • Matched identifier: HKOC_1136754
  • Positioned domains: HAMP 311-361 ; His_kinase 378-455 ; HATPase_c 472-579
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404435#ARA42_RS09170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 485 · GCF_001404435
Assembly13470_2#94 · Scaffoldhaploid
Genome composition3 222 162 bp · 37,5% GCLachnospira eligens
Signal transduction countsGenes 68 · HK 30 · RR 37CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnospira
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnospira

Related genes

Preview from the same derived genome key