Gene detail

ARA42_RS06075

Histidine kinase, CheA

Lachnospira eligens · GCF_001404435

ClassHKTypeCheALength703 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001404435#ARA42_RS06075Stable P2CS identifier used across views.
GenomeGCF_001404435Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnospira
Selected clusterHKOC_0762757Run 6 · 11 sequences · id 100% · cov 80% · representative
External referencesWP_022097331.1 · A0A174YXW2 · MIST4 ARA42_RS06075RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length703 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage427 / 703 aa (60.7%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa703 aa
Hpt: 5-98 aa (94 aa)1H-kinase_dim: 320-384 aa (65 aa)2HATPase_c: 432-571 aa (140 aa)3CheW: 576-703 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-98 aa · 94 aa · 13.4% of protein
Raw tokenHpt:5:4e-20:98:94:84
2 H-kinase_dim#2
320-384 aa · 65 aa · 9.2% of protein
Raw tokenH-kinase_dim:320:6.73e-17:384:67:67
3 HATPase_c#3
432-571 aa · 140 aa · 19.9% of protein
Raw tokenHATPase_c:432:8.84e-18:571:140:109
4 CheW#4
576-703 aa · 128 aa · 18.2% of protein
Raw tokenCheW:576:1.39e-33:703:135:138
  • Raw architecture: Hpt:5:4e-20:98:94:84#H-kinase_dim:320:6.73e-17:384:67:67#HATPase_c:432:8.84e-18:571:140:109#CheW:576:1.39e-33:703:135:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001404435::NZ_CZBU01000003.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span20859-24171Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852490_01250RefSeq proteinWP_022097331.1
Context group IDGCF_001404435::NZ_CZBU01000003.1::G00022
Context members
ARA42_RS06075ARA42_RS06080
Partner locus tags
ARA42_RS06075ARA42_RS06080
Partner old locus tags
ERS852490_01250ERS852490_01251
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022097331.1Primary protein accession used for annex mappings.
UniProt accessionA0A174YXW2Primary UniProt accession resolved in the annex database.
UniProt IDA0A174YXW2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA42_RS06075Primary locus identifier stored in the genes table.
Old locus tagERS852490_01250Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CZBU01000003.1Sequence record reported by the local genomic context database.
Genomic interval20 859-22 970 nt2 112 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span20 859-24 171 ntGCF_001404435::NZ_CZBU01000003.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001404435::NZ_CZBU01000003.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CZBU01000003.1All displayed genes belong to this local TCS context.
Neighborhood span20 859-24 171 nt3 313 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
20 859 nt24 171 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA42_RS06075GCF_001404435#ARA42_RS06075
HKCheACurrent focus

20 859-22 970 nt · Reverse (-)

Old locus ERS852490_01250RefSeq WP_022097331.1
ARA42_RS06080GCF_001404435#ARA42_RS06080
RRCheB

22 972-24 171 nt · Reverse (-)

Old locus ERS852490_01251RefSeq WP_022097332.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0762757Run 6 · HK · 11 sequences
Representative sequenceGCF_001404435#ARA42_RS06075The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0762757

Simplified PFAM architecture for HKOC_0762757

PFAM domain coverage: 502 / 703 aa (71.4%)

1 aa703 aa
Hpt: 5-98 aaHptP2: 185-261 aaP2H-kinase_dim: 319-384 aaH-kinase_dimHATPase_c: 434-571 aaHATPase_cCheW: 576-702 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-98] | P2[185-261] | H-kinase_dim[319-384] | HATPase_c[434-571] | CheW[576-702]
  • Domain count: 5
  • Matched identifier: HKOC_0762757
  • Positioned domains: Hpt 5-98 ; P2 185-261 ; H-kinase_dim 319-384 ; HATPase_c 434-571 ; CheW 576-702
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404435#ARA42_RS06075

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 485 · GCF_001404435
Assembly13470_2#94 · Scaffoldhaploid
Genome composition3 222 162 bp · 37,5% GCLachnospira eligens
Signal transduction countsGenes 68 · HK 30 · RR 37CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnospira
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnospira

Related genes

Preview from the same derived genome key