Gene detail

ADX35_RS09135

Histidine kinase, Classic

Streptococcus pneumoniae · GCF_001084105

ClassHKTypeClassicLength442 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001084105#ADX35_RS09135Stable P2CS identifier used across views.
GenomeGCF_001084105Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_2052406Run 6 · 110 sequences · id 100% · cov 80% · representative
External referencesWP_001865163.1 · A0AA36L6G8 · MIST4 ADX35_RS09135RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length442 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage206 / 442 aa (46.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa442 aa
HAMP: 144-211 aa (68 aa)1HisKA: 231-296 aa (66 aa)2HATPase_c: 344-415 aa (72 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.4% of protein
Raw tokenHAMP:144:0.0000000000296:211:68:69
2 HisKA#2
231-296 aa · 66 aa · 14.9% of protein
Raw tokenHisKA:231:0.000000101:296:66:64
3 HATPase_c#3
344-415 aa · 72 aa · 16.3% of protein
Raw tokenHATPase_c:344:0.0000000000309:415:78:109
  • Raw architecture: HAMP:144:0.0000000000296:211:68:69#HisKA:231:0.000000101:296:66:64#HATPase_c:344:0.0000000000309:415:78:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001084105::NZ_CLIR01000027.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3835-5816Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS022019_01771RefSeq proteinWP_001865163.1
Context group IDGCF_001084105::NZ_CLIR01000027.1::G00011
Context members
ADX35_RS09130ADX35_RS09135
Partner locus tags
ADX35_RS09130ADX35_RS09135
Partner old locus tags
ERS022019_01770ERS022019_01771
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001865163.1Primary protein accession used for annex mappings.
UniProt accessionA0AA36L6G8Primary UniProt accession resolved in the annex database.
UniProt IDA0AA36L6G8_STREEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagADX35_RS09135Primary locus identifier stored in the genes table.
Old locus tagERS022019_01771Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CLIR01000027.1Sequence record reported by the local genomic context database.
Genomic interval4 488-5 816 nt1 329 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 835-5 816 ntGCF_001084105::NZ_CLIR01000027.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001084105::NZ_CLIR01000027.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CLIR01000027.1All displayed genes belong to this local TCS context.
Neighborhood span3 835-5 816 nt1 982 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 835 nt5 816 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ADX35_RS09130GCF_001084105#ADX35_RS09130
RROmpR

3 835-4 491 nt · Forward (+)

Old locus ERS022019_01770RefSeq WP_000697960.1
ADX35_RS09135GCF_001084105#ADX35_RS09135
HKClassicCurrent focus

4 488-5 816 nt · Forward (+)

Old locus ERS022019_01771RefSeq WP_001865163.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2052406Run 6 · HK · 110 sequences
Representative sequenceGCF_001084105#ADX35_RS09135The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2052406

Simplified PFAM architecture for HKOC_2052406

PFAM domain coverage: 198 / 442 aa (44.8%)

1 aa442 aa
HAMP: 162-212 aaHAMPHisKA: 232-295 aaHisKAHATPase_c: 344-426 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[162-212] | HisKA[232-295] | HATPase_c[344-426]
  • Domain count: 3
  • Matched identifier: HKOC_2052406
  • Positioned domains: HAMP 162-212 ; HisKA 232-295 ; HATPase_c 344-426
Cluster members and taxonomy
Visualization

Representative gene: GCF_001084105#ADX35_RS09135

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 313 · GCF_001084105
Assembly6925_7#13 · Scaffoldhaploid
Genome composition2 112 763 bp · 39,5% GCStreptococcus pneumoniae
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key