1 HisKA#1
196-260 aa · 65 aa · 15.6% of protein
Raw token
HisKA:196:0.0000000000203:260:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BN2378_RS00005
Histidine kinase, Classic
Clostridioides difficile · GCF_000826625
ClassHKTypeClassicLength416 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000826625#BN2378_RS00005Stable P2CS identifier used across views.
GenomeGCF_000826625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length416 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 416 aa (41.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
307-415 aa · 109 aa · 26.2% of protein
Raw token
HATPase_c:307:5.38e-18:415:109:109- Raw architecture: HisKA:196:0.0000000000203:260:65:64#HATPase_c:307:5.38e-18:415:109:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000826625::NZ_CDND01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-1899Genomic interval covered by the local TCS group.
Identifiers
Old locus tagUA13_RS00005RefSeq proteinWP_042520356.1
Context group ID
GCF_000826625::NZ_CDND01000001.1::G00001Context members
BN2378_RS00005BN2378_RS00010
Partner locus tags
BN2378_RS00005BN2378_RS00010
Partner old locus tags
UA13_RS00005UA13_RS00010
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_042520356.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBN2378_RS00005Primary locus identifier stored in the genes table.
Old locus tagUA13_RS00005Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CDND01000001.1Sequence record reported by the local genomic context database.
Genomic interval1-1 247 nt1 247 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1-1 899 ntGCF_000826625::NZ_CDND01000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000826625::NZ_CDND01000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CDND01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 899 nt1 899 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 899 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BN2378_RS00005GCF_000826625#BN2378_RS00005
HKClassicCurrent focus
1-1 247 nt · Reverse (-)
BN2378_RS00010GCF_000826625#BN2378_RS00010
RROmpR
1 231-1 899 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000826625#BN2378_RS00005The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2302795
Simplified PFAM architecture for HKOC_2302795
PFAM domain coverage: 171 / 416 aa (41.1%)
1 aa416 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[197-260] | HATPase_c[308-414]
- Domain count: 2
- Matched identifier: HKOC_2302795
- Positioned domains: HisKA 197-260 ; HATPase_c 308-414
Cluster members and taxonomy
Representative gene: GCF_000826625#BN2378_RS00005
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_000826625
AssemblyG46R2_Q2 · Contighaploid
Genome composition4 189 317 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key