Gene detail

BN2378_RS00005

Histidine kinase, Classic

Clostridioides difficile · GCF_000826625

ClassHKTypeClassicLength416 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000826625#BN2378_RS00005Stable P2CS identifier used across views.
GenomeGCF_000826625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2302795Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_042520356.1 · MIST4 BN2378_RS00005RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length416 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 416 aa (41.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BN2378_RS00005
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.6% of protein
Raw tokenHisKA:196:0.0000000000203:260:65:64
2 HATPase_c#2
307-415 aa · 109 aa · 26.2% of protein
Raw tokenHATPase_c:307:5.38e-18:415:109:109
  • Raw architecture: HisKA:196:0.0000000000203:260:65:64#HATPase_c:307:5.38e-18:415:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000826625::NZ_CDND01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-1899Genomic interval covered by the local TCS group.
Identifiers
Old locus tagUA13_RS00005RefSeq proteinWP_042520356.1
Context group IDGCF_000826625::NZ_CDND01000001.1::G00001
Context members
BN2378_RS00005BN2378_RS00010
Partner locus tags
BN2378_RS00005BN2378_RS00010
Partner old locus tags
UA13_RS00005UA13_RS00010
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_042520356.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN2378_RS00005Primary locus identifier stored in the genes table.
Old locus tagUA13_RS00005Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CDND01000001.1Sequence record reported by the local genomic context database.
Genomic interval1-1 247 nt1 247 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1-1 899 ntGCF_000826625::NZ_CDND01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000826625::NZ_CDND01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CDND01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 899 nt1 899 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 899 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN2378_RS00010GCF_000826625#BN2378_RS00010
RROmpR

1 231-1 899 nt · Reverse (-)

Old locus UA13_RS00010RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2302795Run 6 · HK · 1 sequences
Representative sequenceGCF_000826625#BN2378_RS00005The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2302795

Simplified PFAM architecture for HKOC_2302795

PFAM domain coverage: 171 / 416 aa (41.1%)

1 aa416 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-414 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-414]
  • Domain count: 2
  • Matched identifier: HKOC_2302795
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-414
Cluster members and taxonomy
Visualization

Representative gene: GCF_000826625#BN2378_RS00005

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 1 over 1 total members. Page 1 / 1.

GCF_000826625#BN2378_RS00005 (representative)
BN2378_RS00005 · HK · Classic
RefSeq: WP_042520356.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_000826625
AssemblyG46R2_Q2 · Contighaploid
Genome composition4 189 317 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key