1 HAMP#1
193-259 aa · 67 aa · 13.6% of protein
Raw token
HAMP:193:0.0000000275:259:67:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1202_RS08510
Histidine kinase, Classic
[Ruminococcus] lactaris CC59_002D · GCF_000507785
ClassHKTypeClassicLength491 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000507785#HMPREF1202_RS08510Stable P2CS identifier used across views.
GenomeGCF_000507785Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length491 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 491 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa491 aa
Domain-by-domain annotation3 items
2 HisKA#2
264-329 aa · 66 aa · 13.4% of protein
Raw token
HisKA:264:0.00000000000044:329:66:643 HATPase_c#3
377-486 aa · 110 aa · 22.4% of protein
Raw token
HATPase_c:377:1.37e-30:486:110:109- Raw architecture: HAMP:193:0.0000000275:259:67:69#HisKA:264:0.00000000000044:329:66:64#HATPase_c:377:1.37e-30:486:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000507785::NZ_KI669409.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span149387-151508Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1202_01705RefSeq proteinWP_005610261.1
Context group ID
GCF_000507785::NZ_KI669409.1::G00020Context members
HMPREF1202_RS08505HMPREF1202_RS08510
Partner locus tags
HMPREF1202_RS08505HMPREF1202_RS08510
Partner old locus tags
HMPREF1202_01704HMPREF1202_01705
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_005610261.1Primary protein accession used for annex mappings.
UniProt accessionB5CMB2Primary UniProt accession resolved in the annex database.
UniProt IDB5CMB2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1202_RS08510Primary locus identifier stored in the genes table.
Old locus tagHMPREF1202_01705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI669409.1Sequence record reported by the local genomic context database.
Genomic interval150 033-151 508 nt1 476 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span149 387-151 508 ntGCF_000507785::NZ_KI669409.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000507785::NZ_KI669409.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI669409.1All displayed genes belong to this local TCS context.
Neighborhood span149 387-151 508 nt2 122 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
149 387 nt151 508 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1202_RS08505GCF_000507785#HMPREF1202_RS08505
RROmpR
149 387-150 076 nt · Forward (+)
HMPREF1202_RS08510GCF_000507785#HMPREF1202_RS08510
HKClassicCurrent focus
150 033-151 508 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155205#RUMLAC_RS05485Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1527085
Simplified PFAM architecture for HKOC_1527085
PFAM domain coverage: 175 / 491 aa (35.6%)
1 aa491 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[265-329] | HATPase_c[377-486]
- Domain count: 2
- Matched identifier: HKOC_1527085
- Positioned domains: HisKA 265-329 ; HATPase_c 377-486
Cluster members and taxonomy
Representative gene: GCF_000155205#RUMLAC_RS05485
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 073 376 · GCF_000507785
AssemblyRumi_lact_CC59_002D_V1 · Scaffoldhaploid
Genome composition3 086 899 bp · 42,5% GC[Ruminococcus] lactaris CC59_002D
Signal transduction countsGenes 54 · HK 27 · RR 27CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key