1 HAMP#1
94-161 aa · 68 aa · 17.0% of protein
Raw token
HAMP:94:0.00000000479:161:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1202_RS05435
Histidine kinase, Classic
[Ruminococcus] lactaris CC59_002D · GCF_000507785
ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000507785#HMPREF1202_RS05435Stable P2CS identifier used across views.
GenomeGCF_000507785Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage237 / 400 aa (59.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
Domain-by-domain annotation3 items
2 HisKA#2
178-241 aa · 64 aa · 16.0% of protein
Raw token
HisKA:178:0.000000215:241:64:643 HATPase_c#3
286-390 aa · 105 aa · 26.3% of protein
Raw token
HATPase_c:286:0.00000000000000247:390:107:109- Raw architecture: HAMP:94:0.00000000479:161:68:69#HisKA:178:0.000000215:241:64:64#HATPase_c:286:0.00000000000000247:390:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000507785::NZ_KI669408.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span295078-296942Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1202_01093RefSeq proteinWP_008373940.1
Context group ID
GCF_000507785::NZ_KI669408.1::G00014Context members
HMPREF1202_RS05430HMPREF1202_RS05435
Partner locus tags
HMPREF1202_RS05430HMPREF1202_RS05435
Partner old locus tags
HMPREF1202_01092HMPREF1202_01093
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_008373940.1Primary protein accession used for annex mappings.
UniProt accessionA0A414I8X4Primary UniProt accession resolved in the annex database.
UniProt IDA0A414I8X4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1202_RS05435Primary locus identifier stored in the genes table.
Old locus tagHMPREF1202_01093Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI669408.1Sequence record reported by the local genomic context database.
Genomic interval295 740-296 942 nt1 203 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span295 078-296 942 ntGCF_000507785::NZ_KI669408.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000507785::NZ_KI669408.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI669408.1All displayed genes belong to this local TCS context.
Neighborhood span295 078-296 942 nt1 865 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
295 078 nt296 942 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1202_RS05430GCF_000507785#HMPREF1202_RS05430
RROmpR
295 078-295 752 nt · Forward (+)
HMPREF1202_RS05435GCF_000507785#HMPREF1202_RS05435
HKClassicCurrent focus
295 740-296 942 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000507785#HMPREF1202_RS05435The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2441032
Simplified PFAM architecture for HKOC_2441032
PFAM domain coverage: 216 / 400 aa (54.0%)
1 aa400 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[113-161] | HisKA[178-241] | HATPase_c[287-389]
- Domain count: 3
- Matched identifier: HKOC_2441032
- Positioned domains: HAMP 113-161 ; HisKA 178-241 ; HATPase_c 287-389
Cluster members and taxonomy
Representative gene: GCF_000507785#HMPREF1202_RS05435
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 073 376 · GCF_000507785
AssemblyRumi_lact_CC59_002D_V1 · Scaffoldhaploid
Genome composition3 086 899 bp · 42,5% GC[Ruminococcus] lactaris CC59_002D
Signal transduction countsGenes 54 · HK 27 · RR 27CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key