1 HAMP#1
171-240 aa · 70 aa · 14.9% of protein
Raw token
HAMP:171:0.000000000234:240:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1202_RS04865
Histidine kinase, Classic
[Ruminococcus] lactaris CC59_002D · GCF_000507785
ClassHKTypeClassicLength470 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000507785#HMPREF1202_RS04865Stable P2CS identifier used across views.
GenomeGCF_000507785Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length470 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 470 aa (50.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa470 aa
Domain-by-domain annotation3 items
2 HisKA#2
245-304 aa · 60 aa · 12.8% of protein
Raw token
HisKA:245:0.0000000000000774:304:60:643 HATPase_c#3
356-464 aa · 109 aa · 23.2% of protein
Raw token
HATPase_c:356:1.14e-30:464:109:109- Raw architecture: HAMP:171:0.000000000234:240:70:69#HisKA:245:0.0000000000000774:304:60:64#HATPase_c:356:1.14e-30:464:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000507785::NZ_KI669408.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span161514-163660Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1202_00984RefSeq proteinWP_023921439.1
Context group ID
GCF_000507785::NZ_KI669408.1::G00011Context members
HMPREF1202_RS04865HMPREF1202_RS04870
Partner locus tags
HMPREF1202_RS04865HMPREF1202_RS04870
Partner old locus tags
HMPREF1202_00984HMPREF1202_00985
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_023921439.1Primary protein accession used for annex mappings.
UniProt accessionV8C904Primary UniProt accession resolved in the annex database.
UniProt IDV8C904_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1202_RS04865Primary locus identifier stored in the genes table.
Old locus tagHMPREF1202_00984Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI669408.1Sequence record reported by the local genomic context database.
Genomic interval161 514-162 926 nt1 413 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span161 514-163 660 ntGCF_000507785::NZ_KI669408.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000507785::NZ_KI669408.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI669408.1All displayed genes belong to this local TCS context.
Neighborhood span161 514-163 660 nt2 147 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
161 514 nt163 660 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1202_RS04865GCF_000507785#HMPREF1202_RS04865
HKClassicCurrent focus
161 514-162 926 nt · Reverse (-)
HMPREF1202_RS04870GCF_000507785#HMPREF1202_RS04870
RROmpR
162 959-163 660 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000507785#HMPREF1202_RS04865The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1717605
Simplified PFAM architecture for HKOC_1717605
PFAM domain coverage: 217 / 470 aa (46.2%)
1 aa470 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[195-239] | HisKA[246-307] | HATPase_c[357-466]
- Domain count: 3
- Matched identifier: HKOC_1717605
- Positioned domains: HAMP 195-239 ; HisKA 246-307 ; HATPase_c 357-466
Cluster members and taxonomy
Representative gene: GCF_000507785#HMPREF1202_RS04865
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 073 376 · GCF_000507785
AssemblyRumi_lact_CC59_002D_V1 · Scaffoldhaploid
Genome composition3 086 899 bp · 42,5% GC[Ruminococcus] lactaris CC59_002D
Signal transduction countsGenes 54 · HK 27 · RR 27CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key