1 HisKA#1
495-557 aa · 63 aa · 8.7% of protein
Raw token
HisKA:495:4.12e-16:557:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1202_RS02260
Histidine kinase, Classic
[Ruminococcus] lactaris CC59_002D · GCF_000507785
ClassHKTypeClassicLength724 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000507785#HMPREF1202_RS02260Stable P2CS identifier used across views.
GenomeGCF_000507785Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length724 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 724 aa (21.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa724 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
607-701 aa · 95 aa · 13.1% of protein
Raw token
HATPase_c:607:0.0000000000548:701:99:109- Raw architecture: HisKA:495:4.12e-16:557:63:64#HATPase_c:607:0.0000000000548:701:99:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000507785::NZ_KI669407.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span490210-493054Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1202_00455RefSeq proteinWP_023920851.1
Context group ID
GCF_000507785::NZ_KI669407.1::G00004Context members
HMPREF1202_RS02255HMPREF1202_RS02260
Partner locus tags
HMPREF1202_RS02255HMPREF1202_RS02260
Partner old locus tags
HMPREF1202_00454HMPREF1202_00455
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_023920851.1Primary protein accession used for annex mappings.
UniProt accessionV8CEF4Primary UniProt accession resolved in the annex database.
UniProt IDV8CEF4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1202_RS02260Primary locus identifier stored in the genes table.
Old locus tagHMPREF1202_00455Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI669407.1Sequence record reported by the local genomic context database.
Genomic interval490 880-493 054 nt2 175 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span490 210-493 054 ntGCF_000507785::NZ_KI669407.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000507785::NZ_KI669407.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI669407.1All displayed genes belong to this local TCS context.
Neighborhood span490 210-493 054 nt2 845 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
490 210 nt493 054 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1202_RS02255GCF_000507785#HMPREF1202_RS02255
RROmpR
490 210-490 908 nt · Forward (+)
HMPREF1202_RS02260GCF_000507785#HMPREF1202_RS02260
HKClassicCurrent focus
490 880-493 054 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000507785#HMPREF1202_RS02260The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0724627
Simplified PFAM architecture for HKOC_0724627
PFAM domain coverage: 159 / 724 aa (22.0%)
1 aa724 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[495-557] | HATPase_c[607-702]
- Domain count: 2
- Matched identifier: HKOC_0724627
- Positioned domains: HisKA 495-557 ; HATPase_c 607-702
Cluster members and taxonomy
Representative gene: GCF_000507785#HMPREF1202_RS02260
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 073 376 · GCF_000507785
AssemblyRumi_lact_CC59_002D_V1 · Scaffoldhaploid
Genome composition3 086 899 bp · 42,5% GC[Ruminococcus] lactaris CC59_002D
Signal transduction countsGenes 54 · HK 27 · RR 27CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key