1 HAMP#1
273-342 aa · 70 aa · 12.4% of protein
Raw token
HAMP:273:0.000000000000386:342:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS15815
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength564 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000469345#HMPREF0373_RS15815Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length564 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 564 aa (44.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa564 aa
Domain-by-domain annotation3 items
2 His_kinase#2
358-428 aa · 71 aa · 12.6% of protein
Raw token
His_kinase:358:4.62e-26:428:71:803 HATPase_c#3
448-557 aa · 110 aa · 19.5% of protein
Raw token
HATPase_c:448:0.000000000000357:557:119:109- Raw architecture: HAMP:273:0.000000000000386:342:70:69#His_kinase:358:4.62e-26:428:71:80#HATPase_c:448:0.000000000000357:557:119:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000469345::NZ_KI271072.1::G00001
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span75749-77443Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_02365RefSeq proteinWP_021737525.1
Context group ID
GCF_000469345::NZ_KI271072.1::G00001Context members
HMPREF0373_RS15815
Partner locus tags
HMPREF0373_RS15815
Partner old locus tags
HMPREF0373_02365
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021737525.1Primary protein accession used for annex mappings.
UniProt accessionU2PHN6Primary UniProt accession resolved in the annex database.
UniProt IDU2PHN6_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS15815Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_02365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271072.1Sequence record reported by the local genomic context database.
Genomic interval75 749-77 443 nt1 695 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span75 749-77 443 ntGCF_000469345::NZ_KI271072.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271072.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271072.1All displayed genes belong to this local TCS context.
Neighborhood span75 749-77 443 nt1 695 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 749 nt77 443 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF0373_RS15815GCF_000469345#HMPREF0373_RS15815
HKClassicCurrent focus
75 749-77 443 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS15815The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1239942
Simplified PFAM architecture for HKOC_1239942
PFAM domain coverage: 227 / 564 aa (40.2%)
1 aa564 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[291-342] | His_kinase[358-430] | HATPase_c[454-555]
- Domain count: 3
- Matched identifier: HKOC_1239942
- Positioned domains: HAMP 291-342 ; His_kinase 358-430 ; HATPase_c 454-555
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS15815
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key