Gene detail

HMPREF0373_RS15450

Histidine kinase, Classic

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeClassicLength479 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS15450Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1628612Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_021740741.1 · A0A173U2A1 · MIST4 HMPREF0373_RS15450RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length479 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 479 aa (46.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa479 aa
HAMP: 197-264 aa (68 aa)1HisKA: 277-337 aa (61 aa)2HATPase_c: 387-479 aa (93 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
197-264 aa · 68 aa · 14.2% of protein
Raw tokenHAMP:197:0.0000000000114:264:68:69
2 HisKA#2
277-337 aa · 61 aa · 12.7% of protein
Raw tokenHisKA:277:0.00000000000465:337:61:64
3 HATPase_c#3
387-479 aa · 93 aa · 19.4% of protein
Raw tokenHATPase_c:387:0.0000000109:479:109:109
  • Raw architecture: HAMP:197:0.0000000000114:264:68:69#HisKA:277:0.00000000000465:337:61:64#HATPase_c:387:0.0000000109:479:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000469345::NZ_KI271191.1::G00049
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41483-43616Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_02213RefSeq proteinWP_021740741.1
Context group IDGCF_000469345::NZ_KI271191.1::G00049
Context members
HMPREF0373_RS15445HMPREF0373_RS15450
Partner locus tags
HMPREF0373_RS15445HMPREF0373_RS15450
Partner old locus tags
HMPREF0373_02212HMPREF0373_02213
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021740741.1Primary protein accession used for annex mappings.
UniProt accessionA0A173U2A1Primary UniProt accession resolved in the annex database.
UniProt IDA0A173U2A1_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS15450Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_02213Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271191.1Sequence record reported by the local genomic context database.
Genomic interval42 177-43 616 nt1 440 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 483-43 616 ntGCF_000469345::NZ_KI271191.1::G00049

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271191.1::G00049

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271191.1All displayed genes belong to this local TCS context.
Neighborhood span41 483-43 616 nt2 134 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 483 nt43 616 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0373_RS15445GCF_000469345#HMPREF0373_RS15445
RROmpR

41 483-42 193 nt · Forward (+)

Old locus HMPREF0373_02212RefSeq WP_044964955.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1628612Run 6 · HK · 5 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS15450The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1628612

Simplified PFAM architecture for HKOC_1628612

PFAM domain coverage: 102 / 479 aa (21.3%)

1 aa479 aa
HAMP: 223-264 aaHAMPHisKA: 278-337 aaHisKA
HAMPHisKA
  • Simplified architecture: HAMP + HisKA
  • Raw architecture: HAMP[223-264] | HisKA[278-337]
  • Domain count: 2
  • Matched identifier: HKOC_1628612
  • Positioned domains: HAMP 223-264 ; HisKA 278-337
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS15450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key