Gene detail

HMPREF0373_RS14640

Histidine kinase, Hybrid

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeHybridLength957 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS14640Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_0320054Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_044964761.1 · MIST4 HMPREF0373_RS14640RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_cResponse_reg
Protein length957 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage720 / 957 aa (75.2%)Merged over positioned domains only.
Domain description2 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa957 aa
SBP_bac_3: 43-259 aa (217 aa)1SBP_bac_3: 281-482 aa (202 aa)2HisKA: 577-642 aa (66 aa)3HATPase_c: 691-808 aa (118 aa)4Response_reg: 829-945 aa (117 aa)5
Domain-by-domain annotation5 items
1 SBP_bac_3#1
43-259 aa · 217 aa · 22.7% of protein
Raw tokenSBP_bac_3:43:4.44e-26:259:230:224
2 SBP_bac_3#2
281-482 aa · 202 aa · 21.1% of protein
Raw tokenSBP_bac_3:281:3.19e-19:482:215:224
3 HisKA#3
577-642 aa · 66 aa · 6.9% of protein
Raw tokenHisKA:577:3.45e-17:642:66:64
4 HATPase_c#4
691-808 aa · 118 aa · 12.3% of protein
Raw tokenHATPase_c:691:1.02e-26:808:119:109
5 Response_reg#5
829-945 aa · 117 aa · 12.2% of protein
Raw tokenResponse_reg:829:3.54e-30:945:117:111
  • Raw architecture: SBP_bac_3:43:4.44e-26:259:230:224#SBP_bac_3:281:3.19e-19:482:215:224#HisKA:577:3.45e-17:642:66:64#HATPase_c:691:1.02e-26:808:119:109#Response_reg:829:3.54e-30:945:117:111
  • Domain description: 2 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000469345::NZ_KI271185.1::G00047
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span119179-124003Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_02036RefSeq proteinWP_044964761.1
Context group IDGCF_000469345::NZ_KI271185.1::G00047
Context members
HMPREF0373_RS14635HMPREF0373_RS14640
Partner locus tags
HMPREF0373_RS14635HMPREF0373_RS14640
Partner old locus tags
HMPREF0373_02035HMPREF0373_02036
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_044964761.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS14640Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_02036Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271185.1Sequence record reported by the local genomic context database.
Genomic interval121 130-124 003 nt2 874 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span119 179-124 003 ntGCF_000469345::NZ_KI271185.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271185.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271185.1All displayed genes belong to this local TCS context.
Neighborhood span119 179-124 003 nt4 825 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 179 nt124 003 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0373_RS14635GCF_000469345#HMPREF0373_RS14635
HKHybrid

119 179-121 101 nt · Reverse (-)

Old locus HMPREF0373_02035RefSeq WP_021740556.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0320054Run 6 · HK · 2 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS14640The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0320054

Simplified PFAM architecture for HKOC_0320054

PFAM domain coverage: 498 / 957 aa (52.0%)

1 aa957 aa
SBP_bac_3: 51-249 aaSBP_bac_3HisKA: 577-642 aaHisKAHATPase_c: 692-807 aaHATPase_cResponse_reg: 829-945 aaResponse_reg
SBP_bac_3HisKAHATPase_cResponse_reg
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: SBP_bac_3[51-249] | HisKA[577-642] | HATPase_c[692-807] | Response_reg[829-945]
  • Domain count: 4
  • Matched identifier: HKOC_0320054
  • Positioned domains: SBP_bac_3 51-249 ; HisKA 577-642 ; HATPase_c 692-807 ; Response_reg 829-945
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS14640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key