1 HisKA#1
265-331 aa · 67 aa · 10.5% of protein
Raw token
HisKA:265:5.2e-18:331:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS14635
Histidine kinase, Hybrid
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeHybridLength640 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS14635Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length640 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage300 / 640 aa (46.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa640 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
377-495 aa · 119 aa · 18.6% of protein
Raw token
HATPase_c:377:9.52e-31:495:119:1093 Response_reg#3
520-633 aa · 114 aa · 17.8% of protein
Raw token
Response_reg:520:8.21e-29:633:114:111- Raw architecture: HisKA:265:5.2e-18:331:67:64#HATPase_c:377:9.52e-31:495:119:109#Response_reg:520:8.21e-29:633:114:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271185.1::G00047
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span119179-124003Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_02035RefSeq proteinWP_021740556.1
Context group ID
GCF_000469345::NZ_KI271185.1::G00047Context members
HMPREF0373_RS14635HMPREF0373_RS14640
Partner locus tags
HMPREF0373_RS14635HMPREF0373_RS14640
Partner old locus tags
HMPREF0373_02035HMPREF0373_02036
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021740556.1Primary protein accession used for annex mappings.
UniProt accessionU2R4M4Primary UniProt accession resolved in the annex database.
UniProt IDU2R4M4_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS14635Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_02035Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271185.1Sequence record reported by the local genomic context database.
Genomic interval119 179-121 101 nt1 923 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span119 179-124 003 ntGCF_000469345::NZ_KI271185.1::G00047
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271185.1::G00047Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271185.1All displayed genes belong to this local TCS context.
Neighborhood span119 179-124 003 nt4 825 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 179 nt124 003 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS14635GCF_000469345#HMPREF0373_RS14635
HKHybridCurrent focus
119 179-121 101 nt · Reverse (-)
HMPREF0373_RS14640GCF_000469345#HMPREF0373_RS14640
HKHybrid
121 130-124 003 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS14635The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0921178
Simplified PFAM architecture for HKOC_0921178
PFAM domain coverage: 298 / 640 aa (46.6%)
1 aa640 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[265-330] | HATPase_c[378-494] | Response_reg[520-634]
- Domain count: 3
- Matched identifier: HKOC_0921178
- Positioned domains: HisKA 265-330 ; HATPase_c 378-494 ; Response_reg 520-634
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS14635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key