1 PAS_3#1
28-116 aa · 89 aa · 9.6% of protein
Raw token
PAS_3:28:4.71e-21:116:89:89P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS11375
Histidine kinase, Hybrid
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeHybridLength928 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000469345#HMPREF0373_RS11375Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
PAS_3HisKAHATPase_cResponse_reg
Protein length928 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage505 / 928 aa (54.4%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa928 aa
Domain-by-domain annotation5 items
2 HisKA#2
418-484 aa · 67 aa · 7.2% of protein
Raw token
HisKA:418:2.02e-16:484:67:643 HATPase_c#3
531-645 aa · 115 aa · 12.4% of protein
Raw token
HATPase_c:531:3.15e-31:645:115:1094 Response_reg#4
665-781 aa · 117 aa · 12.6% of protein
Raw token
Response_reg:665:2.48e-19:781:117:1115 Response_reg#5
809-925 aa · 117 aa · 12.6% of protein
Raw token
Response_reg:809:8.61e-30:925:117:111- Raw architecture: PAS_3:28:4.71e-21:116:89:89#HisKA:418:2.02e-16:484:67:64#HATPase_c:531:3.15e-31:645:115:109#Response_reg:665:2.48e-19:781:117:111#Response_reg:809:8.61e-30:925:117:111
- Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000469345::NZ_KI271158.1::G00043
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span24712-27498Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_01458RefSeq proteinWP_021739866.1
Context group ID
GCF_000469345::NZ_KI271158.1::G00043Context members
HMPREF0373_RS11375
Partner locus tags
HMPREF0373_RS11375
Partner old locus tags
HMPREF0373_01458
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021739866.1Primary protein accession used for annex mappings.
UniProt accessionU2PTK5Primary UniProt accession resolved in the annex database.
UniProt IDU2PTK5_EUBRADisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS11375Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_01458Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271158.1Sequence record reported by the local genomic context database.
Genomic interval24 712-27 498 nt2 787 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span24 712-27 498 ntGCF_000469345::NZ_KI271158.1::G00043
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271158.1::G00043Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271158.1All displayed genes belong to this local TCS context.
Neighborhood span24 712-27 498 nt2 787 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 712 nt27 498 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF0373_RS11375GCF_000469345#HMPREF0373_RS11375
HKHybridCurrent focus
24 712-27 498 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS11375The current gene is the representative for this cluster.
PFAM architecturePAS_3 + HisKA + HATPase_c + Response_reg + Response_reg5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0355383
Simplified PFAM architecture for HKOC_0355383
PFAM domain coverage: 506 / 928 aa (54.5%)
1 aa928 aa
PAS_3HisKAHATPase_cResponse_regResponse_reg
- Simplified architecture: PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
- Raw architecture: PAS_3[27-116] | HisKA[418-484] | HATPase_c[531-647] | Response_reg[665-780] | Response_reg[809-924]
- Domain count: 5
- Matched identifier: HKOC_0355383
- Positioned domains: PAS_3 27-116 ; HisKA 418-484 ; HATPase_c 531-647 ; Response_reg 665-780 ; Response_reg 809-924
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS11375
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key