1 HAMP#1
154-224 aa · 71 aa · 15.8% of protein
Raw token
HAMP:154:0.0000000000298:224:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS10525
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS10525Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 450 aa (54.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
Domain-by-domain annotation3 items
2 HisKA#2
231-295 aa · 65 aa · 14.4% of protein
Raw token
HisKA:231:0.00000000000000268:295:65:643 HATPase_c#3
339-448 aa · 110 aa · 24.4% of protein
Raw token
HATPase_c:339:6.08e-32:448:110:109- Raw architecture: HAMP:154:0.0000000000298:224:71:69#HisKA:231:0.00000000000000268:295:65:64#HATPase_c:339:6.08e-32:448:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271151.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span42372-44395Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_01320RefSeq proteinWP_021739698.1
Context group ID
GCF_000469345::NZ_KI271151.1::G00040Context members
HMPREF0373_RS10525HMPREF0373_RS10530
Partner locus tags
HMPREF0373_RS10525HMPREF0373_RS10530
Partner old locus tags
HMPREF0373_01320HMPREF0373_01321
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021739698.1Primary protein accession used for annex mappings.
UniProt accessionA0A173VAW8Primary UniProt accession resolved in the annex database.
UniProt IDA0A173VAW8_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS10525Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_01320Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271151.1Sequence record reported by the local genomic context database.
Genomic interval42 372-43 724 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span42 372-44 395 ntGCF_000469345::NZ_KI271151.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271151.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271151.1All displayed genes belong to this local TCS context.
Neighborhood span42 372-44 395 nt2 024 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
42 372 nt44 395 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS10525GCF_000469345#HMPREF0373_RS10525
HKClassicCurrent focus
42 372-43 724 nt · Reverse (-)
HMPREF0373_RS10530GCF_000469345#HMPREF0373_RS10530
RROmpR
43 721-44 395 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS10525The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1962659
Simplified PFAM architecture for HKOC_1962659
PFAM domain coverage: 231 / 450 aa (51.3%)
1 aa450 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[171-224] | HisKA[230-295] | HATPase_c[339-449]
- Domain count: 3
- Matched identifier: HKOC_1962659
- Positioned domains: HAMP 171-224 ; HisKA 230-295 ; HATPase_c 339-449
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS10525
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key