Gene detail

HMPREF0373_RS10060

Histidine kinase, Classic

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeClassicLength295 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000469345#HMPREF0373_RS10060Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_2892170Run 6 · 147 sequences · id 100% · cov 80%
External referencesWP_021739603.1 · U2Q5S2 · MIST4 HMPREF0373_RS10060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length295 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage142 / 295 aa (48.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa295 aa
HisKA: 89-144 aa (56 aa)1HATPase_c: 196-281 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
89-144 aa · 56 aa · 19.0% of protein
Raw tokenHisKA:89:0.000000000018:144:56:64
2 HATPase_c#2
196-281 aa · 86 aa · 29.2% of protein
Raw tokenHATPase_c:196:0.00000000000000256:281:91:109
  • Raw architecture: HisKA:89:0.000000000018:144:56:64#HATPase_c:196:0.00000000000000256:281:91:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000469345::NZ_KI271142.1::G00037
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span284-1171Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00314RefSeq proteinWP_021739603.1
Context group IDGCF_000469345::NZ_KI271142.1::G00037
Context members
HMPREF0373_RS10060
Partner locus tags
HMPREF0373_RS10060
Partner old locus tags
HMPREF0373_00314
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021739603.1Primary protein accession used for annex mappings.
UniProt accessionU2Q5S2Primary UniProt accession resolved in the annex database.
UniProt IDU2Q5S2_EUBRADisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS10060Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00314Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271142.1Sequence record reported by the local genomic context database.
Genomic interval284-1 171 nt888 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span284-1 171 ntGCF_000469345::NZ_KI271142.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271142.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271142.1All displayed genes belong to this local TCS context.
Neighborhood span284-1 171 nt888 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
284 nt1 171 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2892170Run 6 · HK · 147 sequences
Representative sequenceGCF_964272115#ACFY56_RS13685Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2892170

Simplified PFAM architecture for HKOC_2892170

PFAM domain coverage: 144 / 296 aa (48.6%)

1 aa296 aa
HisKA: 88-145 aaHisKAHATPase_c: 197-282 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-145] | HATPase_c[197-282]
  • Domain count: 2
  • Matched identifier: HKOC_2892170
  • Positioned domains: HisKA 88-145 ; HATPase_c 197-282
Cluster members and taxonomy
Visualization

Representative gene: GCF_964272115#ACFY56_RS13685

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key