1 His_kinase#1
431-510 aa · 80 aa · 12.9% of protein
Raw token
His_kinase:431:3.71e-28:510:81:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS09270
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength620 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS09270Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length620 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 620 aa (27.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa620 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
528-618 aa · 91 aa · 14.7% of protein
Raw token
HATPase_c:528:0.000000184:618:106:109- Raw architecture: His_kinase:431:3.71e-28:510:81:80#HATPase_c:528:0.000000184:618:106:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271134.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span75244-78130Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00288RefSeq proteinWP_021739438.1
Context group ID
GCF_000469345::NZ_KI271134.1::G00034Context members
HMPREF0373_RS16060HMPREF0373_RS09270
Partner locus tags
HMPREF0373_RS16060HMPREF0373_RS09270
Partner old locus tags
HMPREF0373_00287HMPREF0373_00288
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021739438.1Primary protein accession used for annex mappings.
UniProt accessionU2RE28Primary UniProt accession resolved in the annex database.
UniProt IDU2RE28_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS09270Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00288Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271134.1Sequence record reported by the local genomic context database.
Genomic interval76 268-78 130 nt1 863 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span75 244-78 130 ntGCF_000469345::NZ_KI271134.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271134.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271134.1All displayed genes belong to this local TCS context.
Neighborhood span75 244-78 130 nt2 887 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 244 nt78 130 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS16060GCF_000469345#HMPREF0373_RS16060
RRunclassified
75 244-76 158 nt · Reverse (-)
HMPREF0373_RS09270GCF_000469345#HMPREF0373_RS09270
HKClassicCurrent focus
76 268-78 130 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS09270The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_0972679
Simplified PFAM architecture for HKOC_0972679
PFAM domain coverage: 80 / 620 aa (12.9%)
1 aa620 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[431-510]
- Domain count: 1
- Matched identifier: HKOC_0972679
- Positioned domains: His_kinase 431-510
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS09270
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key