Gene detail

HMPREF0373_RS08710

Histidine kinase, Classic

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeClassicLength479 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS08710Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1628611Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_021739324.1 · A0A844E563 · MIST4 HMPREF0373_RS08710RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length479 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage240 / 479 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa479 aa
HAMP: 172-241 aa (70 aa)1HisKA: 248-307 aa (60 aa)2HATPase_c: 357-466 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
172-241 aa · 70 aa · 14.6% of protein
Raw tokenHAMP:172:0.0000000000077:241:70:69
2 HisKA#2
248-307 aa · 60 aa · 12.5% of protein
Raw tokenHisKA:248:0.0000000000000054:307:60:64
3 HATPase_c#3
357-466 aa · 110 aa · 23.0% of protein
Raw tokenHATPase_c:357:1.14e-29:466:110:109
  • Raw architecture: HAMP:172:0.0000000000077:241:70:69#HisKA:248:0.0000000000000054:307:60:64#HATPase_c:357:1.14e-29:466:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000469345::NZ_KI271133.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span31711-33872Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_01037RefSeq proteinWP_021739324.1
Context group IDGCF_000469345::NZ_KI271133.1::G00031
Context members
HMPREF0373_RS08705HMPREF0373_RS08710
Partner locus tags
HMPREF0373_RS08705HMPREF0373_RS08710
Partner old locus tags
HMPREF0373_01036HMPREF0373_01037
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021739324.1Primary protein accession used for annex mappings.
UniProt accessionA0A844E563Primary UniProt accession resolved in the annex database.
UniProt IDA0A844E563_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS08710Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_01037Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271133.1Sequence record reported by the local genomic context database.
Genomic interval32 433-33 872 nt1 440 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span31 711-33 872 ntGCF_000469345::NZ_KI271133.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271133.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271133.1All displayed genes belong to this local TCS context.
Neighborhood span31 711-33 872 nt2 162 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
31 711 nt33 872 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0373_RS08705GCF_000469345#HMPREF0373_RS08705
RROmpR

31 711-32 409 nt · Forward (+)

Old locus HMPREF0373_01036RefSeq WP_021739323.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1628611Run 6 · HK · 8 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS08710The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1628611

Simplified PFAM architecture for HKOC_1628611

PFAM domain coverage: 216 / 479 aa (45.1%)

1 aa479 aa
HAMP: 196-240 aaHAMPHisKA: 247-307 aaHisKAHATPase_c: 358-467 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[196-240] | HisKA[247-307] | HATPase_c[358-467]
  • Domain count: 3
  • Matched identifier: HKOC_1628611
  • Positioned domains: HAMP 196-240 ; HisKA 247-307 ; HATPase_c 358-467
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS08710

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key