Gene detail

HMPREF0373_RS07745

Histidine kinase, Classic

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS07745Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1748438Run 6 · 24 sequences · id 100% · cov 80% · representative
External referencesWP_021739123.1 · U2Q7M8 · MIST4 HMPREF0373_RS07745RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage233 / 467 aa (49.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 153-222 aa (70 aa)1HisKA: 251-312 aa (62 aa)2HATPase_c: 358-458 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
153-222 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:153:0.00000000000000636:222:70:69
2 HisKA#2
251-312 aa · 62 aa · 13.3% of protein
Raw tokenHisKA:251:0.0000000118:312:62:64
3 HATPase_c#3
358-458 aa · 101 aa · 21.6% of protein
Raw tokenHATPase_c:358:8.18e-23:458:101:109
  • Raw architecture: HAMP:153:0.00000000000000636:222:70:69#HisKA:251:0.0000000118:312:62:64#HATPase_c:358:8.18e-23:458:101:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000469345::NZ_KI271127.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span55835-57899Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00202RefSeq proteinWP_021739123.1
Context group IDGCF_000469345::NZ_KI271127.1::G00026
Context members
HMPREF0373_RS07740HMPREF0373_RS07745
Partner locus tags
HMPREF0373_RS07740HMPREF0373_RS07745
Partner old locus tags
HMPREF0373_00201HMPREF0373_00202
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021739123.1Primary protein accession used for annex mappings.
UniProt accessionU2Q7M8Primary UniProt accession resolved in the annex database.
UniProt IDU2Q7M8_EUBRADisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS07745Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00202Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271127.1Sequence record reported by the local genomic context database.
Genomic interval56 496-57 899 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span55 835-57 899 ntGCF_000469345::NZ_KI271127.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271127.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271127.1All displayed genes belong to this local TCS context.
Neighborhood span55 835-57 899 nt2 065 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
55 835 nt57 899 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0373_RS07740GCF_000469345#HMPREF0373_RS07740
RROmpR

55 835-56 512 nt · Forward (+)

Old locus HMPREF0373_00201RefSeq WP_021739122.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748438Run 6 · HK · 24 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS07745The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748438

Simplified PFAM architecture for HKOC_1748438

PFAM domain coverage: 217 / 467 aa (46.5%)

1 aa467 aa
HAMP: 170-222 aaHAMPHisKA: 249-312 aaHisKAHATPase_c: 359-458 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[170-222] | HisKA[249-312] | HATPase_c[359-458]
  • Domain count: 3
  • Matched identifier: HKOC_1748438
  • Positioned domains: HAMP 170-222 ; HisKA 249-312 ; HATPase_c 359-458
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS07745

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key