1 HisKA#1
92-153 aa · 62 aa · 20.1% of protein
Raw token
HisKA:92:0.0000000453:153:62:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS07340
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength309 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS07340Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length309 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 309 aa (55.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa309 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
200-307 aa · 108 aa · 35.0% of protein
Raw token
HATPase_c:200:7.3e-29:307:108:109- Raw architecture: HisKA:92:0.0000000453:153:62:64#HATPase_c:200:7.3e-29:307:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271123.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36640-38276Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00038RefSeq proteinWP_021739046.1
Context group ID
GCF_000469345::NZ_KI271123.1::G00025Context members
HMPREF0373_RS07335HMPREF0373_RS07340
Partner locus tags
HMPREF0373_RS07335HMPREF0373_RS07340
Partner old locus tags
HMPREF0373_00037HMPREF0373_00038
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021739046.1Primary protein accession used for annex mappings.
UniProt accessionA0A414UQX9Primary UniProt accession resolved in the annex database.
UniProt IDA0A414UQX9_MEDGNDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS07340Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00038Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271123.1Sequence record reported by the local genomic context database.
Genomic interval37 347-38 276 nt930 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span36 640-38 276 ntGCF_000469345::NZ_KI271123.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271123.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271123.1All displayed genes belong to this local TCS context.
Neighborhood span36 640-38 276 nt1 637 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 640 nt38 276 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS07335GCF_000469345#HMPREF0373_RS07335
RROmpR
36 640-37 341 nt · Forward (+)
HMPREF0373_RS07340GCF_000469345#HMPREF0373_RS07340
HKClassicCurrent focus
37 347-38 276 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS07340The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2879328
Simplified PFAM architecture for HKOC_2879328
PFAM domain coverage: 169 / 309 aa (54.7%)
1 aa309 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[92-152] | HATPase_c[200-307]
- Domain count: 2
- Matched identifier: HKOC_2879328
- Positioned domains: HisKA 92-152 ; HATPase_c 200-307
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS07340
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key