Gene detail

HMPREF0373_RS06255

Histidine kinase, Classic

Eubacterium ramulus ATCC 29099 · GCF_000469345

ClassHKTypeClassicLength354 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000469345#HMPREF0373_RS06255Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_2779427Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_021738813.1 · U2QI43 · MIST4 HMPREF0373_RS06255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length354 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 354 aa (49.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa354 aa
HisKA: 131-194 aa (64 aa)1HATPase_c: 243-352 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
131-194 aa · 64 aa · 18.1% of protein
Raw tokenHisKA:131:0.000000000000103:194:64:64
2 HATPase_c#2
243-352 aa · 110 aa · 31.1% of protein
Raw tokenHATPase_c:243:3.64e-23:352:112:109
  • Raw architecture: HisKA:131:0.000000000000103:194:64:64#HATPase_c:243:3.64e-23:352:112:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000469345::NZ_KI271113.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span25806-26870Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_03360RefSeq proteinWP_021738813.1
Context group IDGCF_000469345::NZ_KI271113.1::G00019
Context members
HMPREF0373_RS06255
Partner locus tags
HMPREF0373_RS06255
Partner old locus tags
HMPREF0373_03360
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021738813.1Primary protein accession used for annex mappings.
UniProt accessionU2QI43Primary UniProt accession resolved in the annex database.
UniProt IDU2QI43_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0373_RS06255Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_03360Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271113.1Sequence record reported by the local genomic context database.
Genomic interval25 806-26 870 nt1 065 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span25 806-26 870 ntGCF_000469345::NZ_KI271113.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000469345::NZ_KI271113.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271113.1All displayed genes belong to this local TCS context.
Neighborhood span25 806-26 870 nt1 065 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 806 nt26 870 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2779427Run 6 · HK · 2 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS06255The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2779427

Simplified PFAM architecture for HKOC_2779427

PFAM domain coverage: 174 / 354 aa (49.2%)

1 aa354 aa
HisKA: 132-195 aaHisKAHATPase_c: 244-353 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[132-195] | HATPase_c[244-353]
  • Domain count: 2
  • Matched identifier: HKOC_2779427
  • Positioned domains: HisKA 132-195 ; HATPase_c 244-353
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS06255

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key