1 HAMP#1
176-245 aa · 70 aa · 14.7% of protein
Raw token
HAMP:176:0.00000989:245:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0373_RS05755
Histidine kinase, Classic
Eubacterium ramulus ATCC 29099 · GCF_000469345
ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000469345#HMPREF0373_RS05755Stable P2CS identifier used across views.
GenomeGCF_000469345Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 475 aa (52.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
Domain-by-domain annotation3 items
2 HisKA#2
249-314 aa · 66 aa · 13.9% of protein
Raw token
HisKA:249:0.00000000000206:314:66:643 HATPase_c#3
362-472 aa · 111 aa · 23.4% of protein
Raw token
HATPase_c:362:2.03e-32:472:111:109- Raw architecture: HAMP:176:0.00000989:245:72:69#HisKA:249:0.00000000000206:314:66:64#HATPase_c:362:2.03e-32:472:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000469345::NZ_KI271109.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21901-24026Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0373_00711RefSeq proteinWP_021738702.1
Context group ID
GCF_000469345::NZ_KI271109.1::G00017Context members
HMPREF0373_RS05750HMPREF0373_RS05755
Partner locus tags
HMPREF0373_RS05750HMPREF0373_RS05755
Partner old locus tags
HMPREF0373_00710HMPREF0373_00711
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021738702.1Primary protein accession used for annex mappings.
UniProt accessionA0A844E4D8Primary UniProt accession resolved in the annex database.
UniProt IDA0A844E4D8_EUBRADisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0373_RS05755Primary locus identifier stored in the genes table.
Old locus tagHMPREF0373_00711Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KI271109.1Sequence record reported by the local genomic context database.
Genomic interval22 599-24 026 nt1 428 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span21 901-24 026 ntGCF_000469345::NZ_KI271109.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000469345::NZ_KI271109.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KI271109.1All displayed genes belong to this local TCS context.
Neighborhood span21 901-24 026 nt2 126 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 901 nt24 026 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF0373_RS05750GCF_000469345#HMPREF0373_RS05750
RROmpR
21 901-22 599 nt · Forward (+)
HMPREF0373_RS05755GCF_000469345#HMPREF0373_RS05755
HKClassicCurrent focus
22 599-24 026 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000469345#HMPREF0373_RS05755The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1664880
Simplified PFAM architecture for HKOC_1664880
PFAM domain coverage: 177 / 475 aa (37.3%)
1 aa475 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[249-314] | HATPase_c[362-472]
- Domain count: 2
- Matched identifier: HKOC_1664880
- Positioned domains: HisKA 249-314 ; HATPase_c 362-472
Cluster members and taxonomy
Representative gene: GCF_000469345#HMPREF0373_RS05755
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 256 908 · GCF_000469345
AssemblyASM46934v1 · Scaffoldhaploid
Genome composition3 447 136 bp · 42,5% GCEubacterium ramulus ATCC 29099
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium
Related genes
Preview from the same derived genome key