Gene detail

QO5_RS03085

Histidine kinase, Classic

Clostridioides difficile F253 · GCF_000450765

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450765#QO5_RS03085Stable P2CS identifier used across views.
GenomeGCF_000450765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2072078Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_330382262.1 · MIST4 QO5_RS03085RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 440 aa (57.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QO5_RS03085
Domain-by-domain annotation3 items
1 HAMP#1
127-204 aa · 78 aa · 17.7% of protein
Raw tokenHAMP:127:0.00000000515:204:78:69
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw tokenHisKA:216:0.00000000144:281:66:64
3 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw tokenHATPase_c:331:1.49e-26:437:107:109
  • Raw architecture: HAMP:127:0.00000000515:204:78:69#HisKA:216:0.00000000144:281:66:64#HATPase_c:331:1.49e-26:437:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450765::NZ_AVKO01000074.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16549-18684Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQO5_0544RefSeq proteinWP_330382262.1
Context group IDGCF_000450765::NZ_AVKO01000074.1::G00006
Context members
QO5_RS03080QO5_RS03085
Partner locus tags
QO5_RS03080QO5_RS03085
Partner old locus tags
QO5_0543QO5_0544
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330382262.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQO5_RS03085Primary locus identifier stored in the genes table.
Old locus tagQO5_0544Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKO01000074.1Sequence record reported by the local genomic context database.
Genomic interval17 362-18 684 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span16 549-18 684 ntGCF_000450765::NZ_AVKO01000074.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450765::NZ_AVKO01000074.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKO01000074.1All displayed genes belong to this local TCS context.
Neighborhood span16 549-18 684 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 549 nt18 684 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QO5_RS03080GCF_000450765#QO5_RS03080
RROmpR

16 549-17 241 nt · Forward (+)

Old locus QO5_0543RefSeq WP_003434748.1
QO5_RS03085GCF_000450765#QO5_RS03085
HKClassicCurrent focus

17 362-18 684 nt · Forward (+)

Old locus QO5_0544RefSeq WP_330382262.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2072078Run 6 · HK · 1 sequences
Representative sequenceGCF_000450765#QO5_RS03085The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2072078

Simplified PFAM architecture for HKOC_2072078

PFAM domain coverage: 223 / 440 aa (50.7%)

1 aa440 aa
HAMP: 154-204 aaHAMPHisKA: 217-281 aaHisKAHATPase_c: 331-437 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
  • Domain count: 3
  • Matched identifier: HKOC_2072078
  • Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450765#QO5_RS03085

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 367 · GCF_000450765
AssemblyASM45076v2 · Contighaploid
Genome composition4 056 592 bp · 28,5% GCClostridioides difficile F253
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key