Gene detail

QO5_RS03160

Histidine kinase, Classic

Clostridioides difficile F253 · GCF_000450765

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000450765#QO5_RS03160Stable P2CS identifier used across views.
GenomeGCF_000450765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783624Run 6 · 384 sequences · id 100% · cov 80%
External referencesWP_009888322.1 · A0A0H3MZ97 · MIST4 QO5_RS03160RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QO5_RS03160
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000177:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000472:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.00000000000000871:439:88:109
  • Raw architecture: HAMP:170:0.00000000000177:237:68:69#HisKA:249:0.000000000472:308:61:64#HATPase_c:355:0.00000000000000871:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000450765::NZ_AVKO01000076.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span180-2214Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQO5_0559RefSeq proteinWP_009888322.1
Context group IDGCF_000450765::NZ_AVKO01000076.1::G00008
Context members
QO5_RS03155QO5_RS03160
Partner locus tags
QO5_RS03155QO5_RS03160
Partner old locus tags
QO5_0558QO5_0559
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009888322.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ97Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ97_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQO5_RS03160Primary locus identifier stored in the genes table.
Old locus tagQO5_0559Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKO01000076.1Sequence record reported by the local genomic context database.
Genomic interval820-2 214 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span180-2 214 ntGCF_000450765::NZ_AVKO01000076.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450765::NZ_AVKO01000076.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKO01000076.1All displayed genes belong to this local TCS context.
Neighborhood span180-2 214 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
180 nt2 214 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QO5_RS03155GCF_000450765#QO5_RS03155
RROmpR

180-827 nt · Forward (+)

Old locus QO5_0558RefSeq WP_021406997.1
QO5_RS03160GCF_000450765#QO5_RS03160
HKClassicCurrent focus

820-2 214 nt · Forward (+)

Old locus QO5_0559RefSeq WP_009888322.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783624Run 6 · HK · 384 sequences
Representative sequenceGCF_000003215#QAC_RS0202630Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783624

Simplified PFAM architecture for HKOC_1783624

PFAM domain coverage: 145 / 464 aa (31.3%)

1 aa464 aa
HisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 2
  • Matched identifier: HKOC_1783624
  • Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 367 · GCF_000450765
AssemblyASM45076v2 · Contighaploid
Genome composition4 056 592 bp · 28,5% GCClostridioides difficile F253
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key