1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw token
HisKA:168:0.0000000000006:234:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QIC_RS18145
Histidine kinase, Classic
Clostridioides difficile DA00044 · GCF_000449905
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449905#QIC_RS18145Stable P2CS identifier used across views.
GenomeGCF_000449905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw token
HATPase_c:280:1.6e-26:388:110:109- Raw architecture: HisKA:168:0.0000000000006:234:67:64#HATPase_c:280:1.6e-26:388:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449905::NZ_AVIS01000143.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10830-12693Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIC_3638RefSeq proteinWP_009903831.1
Context group ID
GCF_000449905::NZ_AVIS01000143.1::G00057Context members
QIC_RS18145QIC_RS18150
Partner locus tags
QIC_RS18145QIC_RS18150
Partner old locus tags
QIC_3638QIC_3639
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009903831.1Primary protein accession used for annex mappings.
UniProt accessionA0A031WHV8Primary UniProt accession resolved in the annex database.
UniProt IDA0A031WHV8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQIC_RS18145Primary locus identifier stored in the genes table.
Old locus tagQIC_3638Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIS01000143.1Sequence record reported by the local genomic context database.
Genomic interval10 830-12 011 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 830-12 693 ntGCF_000449905::NZ_AVIS01000143.1::G00057
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449905::NZ_AVIS01000143.1::G00057Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIS01000143.1All displayed genes belong to this local TCS context.
Neighborhood span10 830-12 693 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 830 nt12 693 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QIC_RS18145GCF_000449905#QIC_RS18145
HKClassicCurrent focus
10 830-12 011 nt · Reverse (-)
QIC_RS18150GCF_000449905#QIC_RS18150
RROmpR
12 001-12 693 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448765#QC5_RS17980Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503575
Simplified PFAM architecture for HKOC_2503575
PFAM domain coverage: 175 / 393 aa (44.5%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[168-233] | HATPase_c[281-389]
- Domain count: 2
- Matched identifier: HKOC_2503575
- Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Representative gene: GCF_000448765#QC5_RS17980
Displayed with 5 columns and 10 rows per page from the local display config.
Showing members 1 to 50 over 299 total members. Page 1 / 6.
GCF_000448765#QC5_RS17980 (representative) | ||||
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 317 · GCF_000449905
AssemblyASM44990v2 · Contighaploid
Genome composition4 059 685 bp · 28,5% GCClostridioides difficile DA00044
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key