Gene detail

BN185_RS17805

Histidine kinase, Classic

Clostridioides difficile E28 · GCF_000530595

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000530595#BN185_RS17805Stable P2CS identifier used across views.
GenomeGCF_000530595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503575Run 6 · 299 sequences · id 100% · cov 80%
External referencesWP_009903831.1 · A0A031WHV8 · MIST4 BN185_RS17805RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 168-234 aa (67 aa)1HATPase_c: 280-388 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw tokenHisKA:168:0.0000000000006:234:67:64
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw tokenHATPase_c:280:1.6e-26:388:110:109
  • Raw architecture: HisKA:168:0.0000000000006:234:67:64#HATPase_c:280:1.6e-26:388:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000530595::NZ_HF923879.1::G00056
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9654-11517Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBN185_2550009RefSeq proteinWP_009903831.1
Context group IDGCF_000530595::NZ_HF923879.1::G00056
Context members
BN185_RS17805BN185_RS17810
Partner locus tags
BN185_RS17805BN185_RS17810
Partner old locus tags
BN185_2550009BN185_2550010
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009903831.1Primary protein accession used for annex mappings.
UniProt accessionA0A031WHV8Primary UniProt accession resolved in the annex database.
UniProt IDA0A031WHV8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBN185_RS17805Primary locus identifier stored in the genes table.
Old locus tagBN185_2550009Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_HF923879.1Sequence record reported by the local genomic context database.
Genomic interval9 654-10 835 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 654-11 517 ntGCF_000530595::NZ_HF923879.1::G00056

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000530595::NZ_HF923879.1::G00056

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_HF923879.1All displayed genes belong to this local TCS context.
Neighborhood span9 654-11 517 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 654 nt11 517 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BN185_RS17805GCF_000530595#BN185_RS17805
HKClassicCurrent focus

9 654-10 835 nt · Reverse (-)

Old locus BN185_2550009RefSeq WP_009903831.1
BN185_RS17810GCF_000530595#BN185_RS17810
RROmpR

10 825-11 517 nt · Reverse (-)

Old locus BN185_2550010RefSeq WP_003435805.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503575Run 6 · HK · 299 sequences
Representative sequenceGCF_000448765#QC5_RS17980Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503575

Simplified PFAM architecture for HKOC_2503575

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503575
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS17980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 215 080 · GCF_000530595
AssemblyE28 · Scaffoldhaploid
Genome composition3 983 867 bp · 28,5% GCClostridioides difficile E28
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key