Gene detail

QIA_RS12190

Histidine kinase, Classic

Clostridioides difficile 6057 · GCF_000449885

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449885#QIA_RS12190Stable P2CS identifier used across views.
GenomeGCF_000449885Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355674Run 6 · 242 sequences · id 100% · cov 80%
External referencesWP_021381512.1 · MIST4 QIA_RS12190RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa530 aa
HisKA: 309-375 aa (67 aa)1HATPase_c: 428-513 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.0000000000000138:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.0000000386:513:90:109
  • Raw architecture: HisKA:309:0.0000000000000138:375:67:64#HATPase_c:428:0.0000000386:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449885::NZ_AVIR01000196.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5161-7438Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIA_2257RefSeq proteinWP_021381512.1
Context group IDGCF_000449885::NZ_AVIR01000196.1::G00039
Context members
QIA_RS12185QIA_RS12190
Partner locus tags
QIA_RS12185QIA_RS12190
Partner old locus tags
QIA_2256QIA_2257
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021381512.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQIA_RS12190Primary locus identifier stored in the genes table.
Old locus tagQIA_2257Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIR01000196.1Sequence record reported by the local genomic context database.
Genomic interval5 846-7 438 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 161-7 438 ntGCF_000449885::NZ_AVIR01000196.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449885::NZ_AVIR01000196.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIR01000196.1All displayed genes belong to this local TCS context.
Neighborhood span5 161-7 438 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 161 nt7 438 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QIA_RS12185GCF_000449885#QIA_RS12185
RROmpR

5 161-5 877 nt · Forward (+)

Old locus QIA_2256RefSeq WP_004454617.1
QIA_RS12190GCF_000449885#QIA_RS12190
HKClassicCurrent focus

5 846-7 438 nt · Forward (+)

Old locus QIA_2257RefSeq WP_021381512.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355674Run 6 · HK · 242 sequences
Representative sequenceGCF_000448725#QAW_RS12370Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355674

Simplified PFAM architecture for HKOC_1355674

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355674
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS12370

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 316 · GCF_000449885
AssemblyASM44988v2 · Contighaploid
Genome composition3 986 776 bp · 28,0% GCClostridioides difficile 6057
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key