1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw token
HisKA:457:0.0000000000000205:524:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QIA_RS12075
Histidine kinase, Classic
Clostridioides difficile 6057 · GCF_000449885
ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449885#QIA_RS12075Stable P2CS identifier used across views.
GenomeGCF_000449885Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw token
HATPase_c:570:0.00000000000182:663:98:109- Raw architecture: HisKA:457:0.0000000000000205:524:68:64#HATPase_c:570:0.00000000000182:663:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449885::NZ_AVIR01000195.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27296-30244Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQIA_2232RefSeq proteinWP_021362720.1
Context group ID
GCF_000449885::NZ_AVIR01000195.1::G00038Context members
QIA_RS12075QIA_RS12085
Partner locus tags
QIA_RS12075QIA_RS12085
Partner old locus tags
QIA_2232QIA_2233
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021362720.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AUA2Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AUA2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQIA_RS12075Primary locus identifier stored in the genes table.
Old locus tagQIA_2232Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIR01000195.1Sequence record reported by the local genomic context database.
Genomic interval27 296-29 356 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 296-30 244 ntGCF_000449885::NZ_AVIR01000195.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449885::NZ_AVIR01000195.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIR01000195.1All displayed genes belong to this local TCS context.
Neighborhood span27 296-30 244 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 296 nt30 244 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QIA_RS12075GCF_000449885#QIA_RS12075
HKClassicCurrent focus
27 296-29 356 nt · Reverse (-)
QIA_RS12085GCF_000449885#QIA_RS12085
RROmpR
29 552-30 244 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448725#QAW_RS12135Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0801035
Simplified PFAM architecture for HKOC_0801035
PFAM domain coverage: 160 / 686 aa (23.3%)
1 aa686 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[457-524] | HATPase_c[571-662]
- Domain count: 2
- Matched identifier: HKOC_0801035
- Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Representative gene: GCF_000448725#QAW_RS12135
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 316 · GCF_000449885
AssemblyASM44988v2 · Contighaploid
Genome composition3 986 776 bp · 28,0% GCClostridioides difficile 6057
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key