Gene detail

QGW_RS02445

Histidine kinase, Classic

Clostridioides difficile 824 · GCF_000449785

ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449785#QGW_RS02445Stable P2CS identifier used across views.
GenomeGCF_000449785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2380250Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_330381647.1 · MIST4 QGW_RS02445RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa407 aa
HAMP: 94-171 aa (78 aa)1HisKA: 183-248 aa (66 aa)2HATPase_c: 298-404 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw tokenHAMP:94:0.0000000106:171:78:69
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw tokenHisKA:183:0.00000000179:248:66:64
3 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw tokenHATPase_c:298:1.66e-26:404:107:109
  • Raw architecture: HAMP:94:0.0000000106:171:78:69#HisKA:183:0.00000000179:248:66:64#HATPase_c:298:1.66e-26:404:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449785::NZ_AVIM01000017.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span62933-65068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQGW_0485RefSeq proteinWP_330381647.1
Context group IDGCF_000449785::NZ_AVIM01000017.1::G00006
Context members
QGW_RS02440QGW_RS02445
Partner locus tags
QGW_RS02440QGW_RS02445
Partner old locus tags
QGW_0484QGW_0485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330381647.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQGW_RS02445Primary locus identifier stored in the genes table.
Old locus tagQGW_0485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVIM01000017.1Sequence record reported by the local genomic context database.
Genomic interval63 845-65 068 nt1 224 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span62 933-65 068 ntGCF_000449785::NZ_AVIM01000017.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449785::NZ_AVIM01000017.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVIM01000017.1All displayed genes belong to this local TCS context.
Neighborhood span62 933-65 068 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
62 933 nt65 068 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QGW_RS02440GCF_000449785#QGW_RS02440
RROmpR

62 933-63 625 nt · Forward (+)

Old locus QGW_0484RefSeq WP_003434748.1
QGW_RS02445GCF_000449785#QGW_RS02445
HKClassicCurrent focus

63 845-65 068 nt · Forward (+)

Old locus QGW_0485RefSeq WP_330381647.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2380250Run 6 · HK · 2 sequences
Representative sequenceGCF_000449785#QGW_RS02445The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2380250

Simplified PFAM architecture for HKOC_2380250

PFAM domain coverage: 223 / 407 aa (54.8%)

1 aa407 aa
HAMP: 121-171 aaHAMPHisKA: 184-248 aaHisKAHATPase_c: 298-404 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[121-171] | HisKA[184-248] | HATPase_c[298-404]
  • Domain count: 3
  • Matched identifier: HKOC_2380250
  • Positioned domains: HAMP 121-171 ; HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449785#QGW_RS02445

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 309 · GCF_000449785
AssemblyASM44978v2 · Contighaploid
Genome composition4 185 643 bp · 28,5% GCClostridioides difficile 824
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key