1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.0000000000000857:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
QCW_RS16415
Histidine kinase, Classic
Clostridioides difficile CD69 · GCF_000449185
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449185#QCW_RS16415Stable P2CS identifier used across views.
GenomeGCF_000449185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:4.62e-25:368:110:109- Raw architecture: HisKA:148:0.0000000000000857:211:64:64#HATPase_c:260:4.62e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000449185::NZ_AVHE01000050.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span101399-103248Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCW_3395RefSeq proteinWP_021376467.1
Context group ID
GCF_000449185::NZ_AVHE01000050.1::G00048Context members
QCW_RS16415QCW_RS16420
Partner locus tags
QCW_RS16415QCW_RS16420
Partner old locus tags
QCW_3395QCW_3396
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021376467.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagQCW_RS16415Primary locus identifier stored in the genes table.
Old locus tagQCW_3395Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVHE01000050.1Sequence record reported by the local genomic context database.
Genomic interval101 399-102 514 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span101 399-103 248 ntGCF_000449185::NZ_AVHE01000050.1::G00048
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000449185::NZ_AVHE01000050.1::G00048Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVHE01000050.1All displayed genes belong to this local TCS context.
Neighborhood span101 399-103 248 nt1 850 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
101 399 nt103 248 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
QCW_RS16415GCF_000449185#QCW_RS16415
HKClassicCurrent focus
101 399-102 514 nt · Reverse (-)
QCW_RS16420GCF_000449185#QCW_RS16420
RROmpR
102 550-103 248 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449185#QCW_RS16415The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2676373
Simplified PFAM architecture for HKOC_2676373
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2676373
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_000449185#QCW_RS16415
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 151 274 · GCF_000449185
AssemblyASM44918v2 · Contighaploid
Genome composition3 991 067 bp · 28,5% GCClostridioides difficile CD69
Signal transduction countsGenes 95 · HK 43 · RR 50CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key