Gene detail

QCK_RS12460

Response regulator OmpR family

Clostridioides difficile CD45 · GCF_000449065

ClassRRTypeOmpRLength222 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449065#QCK_RS12460Stable P2CS identifier used across views.
GenomeGCF_000449065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1637271Run 7 · 2958 sequences · id 100% · cov 80%
External referencesWP_003424455.1 · D5Q3K0 · MIST4 QCK_RS12460RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length222 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage182 / 222 aa (82.0%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCK_RS12460
Domain-by-domain annotation2 items
1 Response_reg#1
5-114 aa · 110 aa · 49.5% of protein
Raw tokenResponse_reg:5:3.32e-34:114:111:111
2 Trans_reg_C#2
147-218 aa · 72 aa · 32.4% of protein
Raw tokenTrans_reg_C:147:1.02e-29:218:77:77
  • Raw architecture: Response_reg:5:3.32e-34:114:111:111#Trans_reg_C:147:1.02e-29:218:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449065::NZ_AVGY01000122.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span850-2779Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCK_2235RefSeq proteinWP_003424455.1
Context group IDGCF_000449065::NZ_AVGY01000122.1::G00035
Context members
QCK_RS12455QCK_RS12460
Partner locus tags
QCK_RS12455QCK_RS12460
Partner old locus tags
QCK_2234QCK_2235
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424455.1Primary protein accession used for annex mappings.
UniProt accessionD5Q3K0Primary UniProt accession resolved in the annex database.
UniProt IDD5Q3K0_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCK_RS12460Primary locus identifier stored in the genes table.
Old locus tagQCK_2235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGY01000122.1Sequence record reported by the local genomic context database.
Genomic interval2 111-2 779 nt669 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span850-2 779 ntGCF_000449065::NZ_AVGY01000122.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449065::NZ_AVGY01000122.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGY01000122.1All displayed genes belong to this local TCS context.
Neighborhood span850-2 779 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
850 nt2 779 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCK_RS12455GCF_000449065#QCK_RS12455
HKClassic

850-2 127 nt · Reverse (-)

Old locus QCK_2234RefSeq WP_003434036.1
QCK_RS12460GCF_000449065#QCK_RS12460
RROmpRCurrent focus

2 111-2 779 nt · Reverse (-)

Old locus QCK_2235RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1637271Run 7 · RR · 2958 sequences
Representative sequenceGCF_000003215#QAC_RS0210665Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1637271

Simplified PFAM architecture for RROC_1637271

PFAM domain coverage: 182 / 222 aa (82.0%)

1 aa222 aa
Response_reg: 5-114 aaResponse_regResponse_reg: 5-114 aaResponse_regTrans_reg_C: 147-218 aaTrans_reg_CTrans_reg_C: 147-218 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[5-114] | Trans_reg_C[147-218]
  • Domain count: 2
  • Matched identifier: RROC_1637271
  • Positioned domains: Response_reg 5-114 ; Response_reg 5-114 ; Trans_reg_C 147-218 ; Trans_reg_C 147-218
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0210665

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 268 · GCF_000449065
AssemblyASM44906v2 · Contighaploid
Genome composition4 367 906 bp · 28,5% GCClostridioides difficile CD45
Signal transduction countsGenes 98 · HK 46 · RR 51CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key