Gene detail

QCK_RS02545

Histidine kinase, Classic

Clostridioides difficile CD45 · GCF_000449065

ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449065#QCK_RS02545Stable P2CS identifier used across views.
GenomeGCF_000449065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2328113Run 6 · 904 sequences · id 100% · cov 80%
External referencesWP_009895239.1 · A0A069APN2 · MIST4 QCK_RS02545RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 413 aa (40.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCK_RS02545
Domain-by-domain annotation2 items
1 HisKA#1
195-255 aa · 61 aa · 14.8% of protein
Raw tokenHisKA:195:0.000000000000205:255:61:64
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw tokenHATPase_c:302:1.59e-25:407:106:109
  • Raw architecture: HisKA:195:0.000000000000205:255:61:64#HATPase_c:302:1.59e-25:407:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449065::NZ_AVGY01000036.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6083-8021Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCK_0182RefSeq proteinWP_009895239.1
Context group IDGCF_000449065::NZ_AVGY01000036.1::G00002
Context members
QCK_RS02540QCK_RS02545
Partner locus tags
QCK_RS02540QCK_RS02545
Partner old locus tags
QCK_0181QCK_0182
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009895239.1Primary protein accession used for annex mappings.
UniProt accessionA0A069APN2Primary UniProt accession resolved in the annex database.
UniProt IDA0A069APN2_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCK_RS02545Primary locus identifier stored in the genes table.
Old locus tagQCK_0182Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGY01000036.1Sequence record reported by the local genomic context database.
Genomic interval6 780-8 021 nt1 242 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 083-8 021 ntGCF_000449065::NZ_AVGY01000036.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449065::NZ_AVGY01000036.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGY01000036.1All displayed genes belong to this local TCS context.
Neighborhood span6 083-8 021 nt1 939 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 083 nt8 021 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCK_RS02540GCF_000449065#QCK_RS02540
RROmpR

6 083-6 769 nt · Forward (+)

Old locus QCK_0181RefSeq WP_009901675.1
QCK_RS02545GCF_000449065#QCK_RS02545
HKClassicCurrent focus

6 780-8 021 nt · Forward (+)

Old locus QCK_0182RefSeq WP_009895239.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2328113Run 6 · HK · 904 sequences
Representative sequenceGCF_000154625#QAB_RS0203230Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2328113

Simplified PFAM architecture for HKOC_2328113

PFAM domain coverage: 172 / 413 aa (41.6%)

1 aa413 aa
HisKA: 193-255 aaHisKAHATPase_c: 302-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[193-255] | HATPase_c[302-410]
  • Domain count: 2
  • Matched identifier: HKOC_2328113
  • Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0203230

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 268 · GCF_000449065
AssemblyASM44906v2 · Contighaploid
Genome composition4 367 906 bp · 28,5% GCClostridioides difficile CD45
Signal transduction countsGenes 98 · HK 46 · RR 51CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key