Gene detail

QCG_RS10570

Histidine kinase, Classic

Clostridioides difficile CD43 · GCF_000449025

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000449025#QCG_RS10570Stable P2CS identifier used across views.
GenomeGCF_000449025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827963Run 6 · 98 sequences · id 100% · cov 80% · representative
External referencesWP_021370409.1 · MIST4 QCG_RS10570RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QCG_RS10570
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000299:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:4.45e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000299:189:66:64#HATPase_c:241:4.45e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000449025::NZ_AVGW01000061.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span66816-68523Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQCG_2141RefSeq proteinWP_021370409.1
Context group IDGCF_000449025::NZ_AVGW01000061.1::G00035
Context members
QCG_RS10565QCG_RS10570
Partner locus tags
QCG_RS10565QCG_RS10570
Partner old locus tags
QCG_2140QCG_2141
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021370409.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQCG_RS10570Primary locus identifier stored in the genes table.
Old locus tagQCG_2141Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGW01000061.1Sequence record reported by the local genomic context database.
Genomic interval67 492-68 523 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span66 816-68 523 ntGCF_000449025::NZ_AVGW01000061.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000449025::NZ_AVGW01000061.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGW01000061.1All displayed genes belong to this local TCS context.
Neighborhood span66 816-68 523 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
66 816 nt68 523 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QCG_RS10565GCF_000449025#QCG_RS10565
RROmpR

66 816-67 502 nt · Forward (+)

Old locus QCG_2140RefSeq WP_009897092.1
QCG_RS10570GCF_000449025#QCG_RS10570
HKClassicCurrent focus

67 492-68 523 nt · Forward (+)

Old locus QCG_2141RefSeq WP_021370409.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827963Run 6 · HK · 98 sequences
Representative sequenceGCF_000449025#QCG_RS10570The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827963

Simplified PFAM architecture for HKOC_2827963

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827963
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449025#QCG_RS10570

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 266 · GCF_000449025
AssemblyASM44902v2 · Contighaploid
Genome composition4 329 033 bp · 28,0% GCClostridioides difficile CD43
Signal transduction countsGenes 99 · HK 46 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key