Gene detail

QC5_RS12975

Histidine kinase, Classic

Clostridioides difficile CD34 · GCF_000448765

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448765#QC5_RS12975Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0599068Run 6 · 87 sequences · id 100% · cov 80% · representative
External referencesWP_231302831.1 · A0A069AJ28 · MIST4 QC5_RS12975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QC5_RS12975
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.35e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000407:775:110:109
  • Raw architecture: HisKA:558:1.35e-18:624:67:64#HATPase_c:671:0.000000000407:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448765::NZ_AVGQ01000037.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span550493-553517Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_2615RefSeq proteinWP_231302831.1
Context group IDGCF_000448765::NZ_AVGQ01000037.1::G00042
Context members
QC5_RS12975QC5_RS12980
Partner locus tags
QC5_RS12975QC5_RS12980
Partner old locus tags
QC5_2615QC5_2616
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_231302831.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AJ28Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AJ28_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC5_RS12975Primary locus identifier stored in the genes table.
Old locus tagQC5_2615Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000037.1Sequence record reported by the local genomic context database.
Genomic interval550 493-552 829 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span550 493-553 517 ntGCF_000448765::NZ_AVGQ01000037.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448765::NZ_AVGQ01000037.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000037.1All displayed genes belong to this local TCS context.
Neighborhood span550 493-553 517 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
550 493 nt553 517 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC5_RS12975GCF_000448765#QC5_RS12975
HKClassicCurrent focus

550 493-552 829 nt · Reverse (-)

Old locus QC5_2615RefSeq WP_231302831.1
QC5_RS12980GCF_000448765#QC5_RS12980
RROmpR

552 801-553 517 nt · Reverse (-)

Old locus QC5_2616RefSeq WP_003431132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0599068Run 6 · HK · 87 sequences
Representative sequenceGCF_000448765#QC5_RS12975The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0599068

Simplified PFAM architecture for HKOC_0599068

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0599068
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS12975

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key