Gene detail

QC5_RS07175

Histidine kinase, Classic

Clostridioides difficile CD34 · GCF_000448765

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448765#QC5_RS07175Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293767Run 6 · 98 sequences · id 100% · cov 80% · representative
External referencesWP_074037295.1 · MIST4 QC5_RS07175RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QC5_RS07175
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.00000000127:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:2.22e-21:410:107:109
  • Raw architecture: HisKA:199:0.00000000127:258:60:64#HATPase_c:304:2.22e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448765::NZ_AVGQ01000028.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span444744-446679Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_1440RefSeq proteinWP_074037295.1
Context group IDGCF_000448765::NZ_AVGQ01000028.1::G00020
Context members
QC5_RS07170QC5_RS07175
Partner locus tags
QC5_RS07170QC5_RS07175
Partner old locus tags
QC5_1439QC5_1440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074037295.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC5_RS07175Primary locus identifier stored in the genes table.
Old locus tagQC5_1440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000028.1Sequence record reported by the local genomic context database.
Genomic interval445 426-446 679 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span444 744-446 679 ntGCF_000448765::NZ_AVGQ01000028.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448765::NZ_AVGQ01000028.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000028.1All displayed genes belong to this local TCS context.
Neighborhood span444 744-446 679 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
444 744 nt446 679 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC5_RS07170GCF_000448765#QC5_RS07170
RROmpR

444 744-445 448 nt · Forward (+)

Old locus QC5_1439RefSeq WP_011861224.1
QC5_RS07175GCF_000448765#QC5_RS07175
HKClassicCurrent focus

445 426-446 679 nt · Forward (+)

Old locus QC5_1440RefSeq WP_074037295.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293767Run 6 · HK · 98 sequences
Representative sequenceGCF_000448765#QC5_RS07175The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293767

Simplified PFAM architecture for HKOC_2293767

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293767
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS07175

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key