Gene detail

QC1_RS12135

Histidine kinase, Classic

Clostridioides difficile CD21 · GCF_000448745

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448745#QC1_RS12135Stable P2CS identifier used across views.
GenomeGCF_000448745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0801035Run 6 · 765 sequences · id 100% · cov 80%
External referencesWP_021362720.1 · A0A069AUA2 · MIST4 QC1_RS12135RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
HisKA: 457-524 aa (68 aa)1HATPase_c: 570-663 aa (94 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000205:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000182:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000205:524:68:64#HATPase_c:570:0.00000000000182:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448745::NZ_AVGO01000104.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span26783-29731Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC1_2375RefSeq proteinWP_021362720.1
Context group IDGCF_000448745::NZ_AVGO01000104.1::G00039
Context members
QC1_RS12135QC1_RS12145
Partner locus tags
QC1_RS12135QC1_RS12145
Partner old locus tags
QC1_2375QC1_2376
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021362720.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AUA2Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AUA2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC1_RS12135Primary locus identifier stored in the genes table.
Old locus tagQC1_2375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGO01000104.1Sequence record reported by the local genomic context database.
Genomic interval26 783-28 843 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span26 783-29 731 ntGCF_000448745::NZ_AVGO01000104.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448745::NZ_AVGO01000104.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGO01000104.1All displayed genes belong to this local TCS context.
Neighborhood span26 783-29 731 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 783 nt29 731 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC1_RS12135GCF_000448745#QC1_RS12135
HKClassicCurrent focus

26 783-28 843 nt · Reverse (-)

Old locus QC1_2375RefSeq WP_021362720.1
QC1_RS12145GCF_000448745#QC1_RS12145
RROmpR

29 039-29 731 nt · Reverse (-)

Old locus QC1_2376RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0801035Run 6 · HK · 765 sequences
Representative sequenceGCF_000448725#QAW_RS12135Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0801035

Simplified PFAM architecture for HKOC_0801035

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0801035
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS12135

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 765 total members. Page 1 / 16.

GCF_000448725#QAW_RS12135 (representative)
QAW_RS12135 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000448745#QC1_RS12135
QC1_RS12135 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000448765#QC5_RS11580
QC5_RS11580 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000448805#QKI_RS12540
QKI_RS12540 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000448925#QC7_RS11985
QC7_RS11985 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449085#QCM_RS10830
QCM_RS10830 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449125#QCQ_RS12010
QCQ_RS12010 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449145#QCS_RS11255
QCS_RS11255 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449165#QCU_RS11180
QCU_RS11180 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449205#QMQ_RS11750
QMQ_RS11750 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449225#QCY_RS11760
QCY_RS11760 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449245#QEA_RS11970
QEA_RS11970 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449345#QEO_RS11775
QEO_RS11775 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449365#QEQ_RS11760
QEQ_RS11760 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449485#QG3_RS12055
QG3_RS12055 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449505#QG5_RS12565
QG5_RS12565 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449545#QG9_RS11325
QG9_RS11325 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449705#QGM_RS11600
QGM_RS11600 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449765#QGU_RS11970
QGU_RS11970 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449805#QGY_RS11360
QGY_RS11360 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449825#QI3_RS11780
QI3_RS11780 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449865#QI7_RS14645
QI7_RS14645 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449885#QIA_RS12075
QIA_RS12075 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449925#QIE_RS11725
QIE_RS11725 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000449965#QII_RS11635
QII_RS11635 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450045#QIS_RS12090
QIS_RS12090 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450065#QIU_RS11745
QIU_RS11745 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450085#QIW_RS12155
QIW_RS12155 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450105#QIY_RS11520
QIY_RS11520 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450265#QKE_RS11910
QKE_RS11910 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450425#QKW_RS11865
QKW_RS11865 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450485#QM3_RS11405
QM3_RS11405 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450505#QM5_RS11605
QM5_RS11605 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450525#QM7_RS11360
QM7_RS11360 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450565#QMA_RS11695
QMA_RS11695 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450585#QMC_RS11305
QMC_RS11305 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450605#QME_RS12805
QME_RS12805 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450645#QSA_RS11905
QSA_RS11905 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450705#QMW_RS11920
QMW_RS11920 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450825#QOG_RS11275
QOG_RS11275 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450845#QOI_RS11235
QOI_RS11235 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450865#QOK_RS12465
QOK_RS12465 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450885#QOM_RS11090
QOM_RS11090 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000450905#QQI_RS10905
QQI_RS10905 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451085#QSE_RS12775
QSE_RS12775 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451105#QSG_RS12855
QSG_RS12855 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451145#QQ1_RS11040
QQ1_RS11040 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451205#QE5_RS11885
QE5_RS11885 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451285#QEC_RS11545
QEC_RS11545 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2
GCF_000451365#QOO_RS13140
QOO_RS13140 · HK · Classic
RefSeq: WP_021362720.1
UniProt: A0A069AUA2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 258 · GCF_000448745
AssemblyASM44874v2 · Contighaploid
Genome composition4 041 992 bp · 28,5% GCClostridioides difficile CD21
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key