Gene detail

G605_RS0110725

Histidine kinase, Classic

Clostridium cadaveris AGR2141 · GCF_000424205

ClassHKTypeClassicLength596 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000424205#G605_RS0110725Stable P2CS identifier used across views.
GenomeGCF_000424205Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1073775Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_027639186.1 · A0A1I2N265 · MIST4 G605_RS0110725RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length596 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage419 / 596 aa (70.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa596 aa
dCache_1: 122-281 aa (160 aa)1HAMP: 300-368 aa (69 aa)2His_kinase: 384-463 aa (80 aa)3HATPase_c: 475-584 aa (110 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
122-281 aa · 160 aa · 26.8% of protein
Raw tokendCache_1:122:0.00000000000000425:281:165:195
2 HAMP#2
300-368 aa · 69 aa · 11.6% of protein
Raw tokenHAMP:300:0.000000000422:368:69:69
3 His_kinase#3
384-463 aa · 80 aa · 13.4% of protein
Raw tokenHis_kinase:384:5.7e-35:463:80:80
4 HATPase_c#4
475-584 aa · 110 aa · 18.5% of protein
Raw tokenHATPase_c:475:0.00000000000000519:584:113:109
  • Raw architecture: dCache_1:122:0.00000000000000425:281:165:195#HAMP:300:0.000000000422:368:69:69#His_kinase:384:5.7e-35:463:80:80#HATPase_c:475:0.00000000000000519:584:113:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000424205::NZ_AUJL01000021.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15084-18480Genomic interval covered by the local TCS group.
Context group IDGCF_000424205::NZ_AUJL01000021.1::G00037
Context members
G605_RS0110725G605_RS0110730
Partner locus tags
G605_RS0110725G605_RS0110730
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_027639186.1Primary protein accession used for annex mappings.
UniProt accessionA0A1I2N265Primary UniProt accession resolved in the annex database.
UniProt IDA0A1I2N265_9CLOTDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG605_RS0110725Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AUJL01000021.1Sequence record reported by the local genomic context database.
Genomic interval15 084-16 874 nt1 791 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 084-18 480 ntGCF_000424205::NZ_AUJL01000021.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000424205::NZ_AUJL01000021.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AUJL01000021.1All displayed genes belong to this local TCS context.
Neighborhood span15 084-18 480 nt3 397 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 084 nt18 480 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G605_RS0110730GCF_000424205#G605_RS0110730
RRunclassified

16 885-18 480 nt · Reverse (-)

RefSeq WP_027639187.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1073775Run 6 · HK · 6 sequences
Representative sequenceGCF_000424205#G605_RS0110725The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1073775

Simplified PFAM architecture for HKOC_1073775

PFAM domain coverage: 473 / 596 aa (79.4%)

1 aa596 aa
dCache_1: 49-281 aadCache_1HAMP: 317-368 aaHAMPHis_kinase: 384-463 aaHis_kinaseHATPase_c: 477-584 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[49-281] | HAMP[317-368] | His_kinase[384-463] | HATPase_c[477-584]
  • Domain count: 4
  • Matched identifier: HKOC_1073775
  • Positioned domains: dCache_1 49-281 ; HAMP 317-368 ; His_kinase 384-463 ; HATPase_c 477-584
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424205#G605_RS0110725

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 280 692 · GCF_000424205
AssemblyASM42420v1 · Scaffoldhaploid
Genome composition3 542 160 bp · 31,0% GCClostridium cadaveris AGR2141
Signal transduction countsGenes 80 · HK 39 · RR 40CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key