Gene detail

G605_RS0104615

Histidine kinase, Classic

Clostridium cadaveris AGR2141 · GCF_000424205

ClassHKTypeClassicLength562 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000424205#G605_RS0104615Stable P2CS identifier used across views.
GenomeGCF_000424205Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_1249340Run 6 · 11 sequences · id 100% · cov 80% · representative
External referencesWP_027638123.1 · A0A1I2JEL3 · MIST4 G605_RS0104615RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAF_3His_kinaseHATPase_c
Protein length562 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage294 / 562 aa (52.3%)Merged over positioned domains only.
Domain description1 GAF_3,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa562 aa
GAF_3: 220-345 aa (126 aa)1His_kinase: 359-437 aa (79 aa)2HATPase_c: 460-548 aa (89 aa)3
Domain-by-domain annotation3 items
1 GAF_3#1
220-345 aa · 126 aa · 22.4% of protein
Raw tokenGAF_3:220:0.000000046:345:131:129
2 His_kinase#2
359-437 aa · 79 aa · 14.1% of protein
Raw tokenHis_kinase:359:4.35e-31:437:80:80
3 HATPase_c#3
460-548 aa · 89 aa · 15.8% of protein
Raw tokenHATPase_c:460:0.000000000124:548:96:109
  • Raw architecture: GAF_3:220:0.000000046:345:131:129#His_kinase:359:4.35e-31:437:80:80#HATPase_c:460:0.000000000124:548:96:109
  • Domain description: 1 GAF_3,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000424205::NZ_AUJL01000006.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span75325-77701Genomic interval covered by the local TCS group.
Context group IDGCF_000424205::NZ_AUJL01000006.1::G00013
Context members
G605_RS0104610G605_RS0104615
Partner locus tags
G605_RS0104610G605_RS0104615
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_027638123.1Primary protein accession used for annex mappings.
UniProt accessionA0A1I2JEL3Primary UniProt accession resolved in the annex database.
UniProt IDA0A1I2JEL3_9CLOTDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG605_RS0104615Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AUJL01000006.1Sequence record reported by the local genomic context database.
Genomic interval76 013-77 701 nt1 689 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span75 325-77 701 ntGCF_000424205::NZ_AUJL01000006.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000424205::NZ_AUJL01000006.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AUJL01000006.1All displayed genes belong to this local TCS context.
Neighborhood span75 325-77 701 nt2 377 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 325 nt77 701 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1249340Run 6 · HK · 11 sequences
Representative sequenceGCF_000424205#G605_RS0104615The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + GAF_2 + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1249340

Simplified PFAM architecture for HKOC_1249340

PFAM domain coverage: 456 / 562 aa (81.1%)

1 aa562 aa
5TM-5TMR_LYT: 28-188 aa5TM-5TMR_LYTGAF_2: 222-342 aaGAF_2His_kinase: 359-437 aaHis_kinaseHATPase_c: 457-551 aaHATPase_c
5TM-5TMR_LYTGAF_2His_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + GAF_2 + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[28-188] | GAF_2[222-342] | His_kinase[359-437] | HATPase_c[457-551]
  • Domain count: 4
  • Matched identifier: HKOC_1249340
  • Positioned domains: 5TM-5TMR_LYT 28-188 ; GAF_2 222-342 ; His_kinase 359-437 ; HATPase_c 457-551
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424205#G605_RS0104615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 280 692 · GCF_000424205
AssemblyASM42420v1 · Scaffoldhaploid
Genome composition3 542 160 bp · 31,0% GCClostridium cadaveris AGR2141
Signal transduction countsGenes 80 · HK 39 · RR 40CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key