Gene detail

II1_RS04225

Histidine kinase, Classic

Bacillus cereus MC118 · GCF_000399245

ClassHKTypeClassicLength456 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000399245#II1_RS04225Stable P2CS identifier used across views.
GenomeGCF_000399245Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1887964Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_002161190.1 · J8F6Y5 · MIST4 II1_RS04225RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length456 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 456 aa (54.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for II1_RS04225
Domain-by-domain annotation3 items
1 HAMP#1
155-226 aa · 72 aa · 15.8% of protein
Raw tokenHAMP:155:0.000000000000625:226:72:69
2 HisKA#2
233-296 aa · 64 aa · 14.0% of protein
Raw tokenHisKA:233:0.000000000000153:296:64:64
3 HATPase_c#3
341-454 aa · 114 aa · 25.0% of protein
Raw tokenHATPase_c:341:1.15e-27:454:114:109
  • Raw architecture: HAMP:155:0.000000000000625:226:72:69#HisKA:233:0.000000000000153:296:64:64#HATPase_c:341:1.15e-27:454:114:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000399245::NZ_KB976368.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5027-7068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagII1_05522RefSeq proteinWP_002161190.1
Context group IDGCF_000399245::NZ_KB976368.1::G00006
Context members
II1_RS04225II1_RS04230
Partner locus tags
II1_RS04225II1_RS04230
Partner old locus tags
II1_05522II1_05523
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002161190.1Primary protein accession used for annex mappings.
UniProt accessionJ8F6Y5Primary UniProt accession resolved in the annex database.
UniProt IDJ8F6Y5_BACCEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagII1_RS04225Primary locus identifier stored in the genes table.
Old locus tagII1_05522Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB976368.1Sequence record reported by the local genomic context database.
Genomic interval5 027-6 397 nt1 371 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 027-7 068 ntGCF_000399245::NZ_KB976368.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000399245::NZ_KB976368.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB976368.1All displayed genes belong to this local TCS context.
Neighborhood span5 027-7 068 nt2 042 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 027 nt7 068 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

II1_RS04225GCF_000399245#II1_RS04225
HKClassicCurrent focus

5 027-6 397 nt · Reverse (-)

Old locus II1_05522RefSeq WP_002161190.1
II1_RS04230GCF_000399245#II1_RS04230
RROmpR

6 394-7 068 nt · Reverse (-)

Old locus II1_05523RefSeq WP_002161191.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1887964Run 6 · HK · 2 sequences
Representative sequenceGCF_000291155#II3_RS21925Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1887964

Simplified PFAM architecture for HKOC_1887964

PFAM domain coverage: 232 / 456 aa (50.9%)

1 aa456 aa
HAMP: 171-225 aaHAMPHisKA: 232-296 aaHisKAHATPase_c: 342-453 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[171-225] | HisKA[232-296] | HATPase_c[342-453]
  • Domain count: 3
  • Matched identifier: HKOC_1887964
  • Positioned domains: HAMP 171-225 ; HisKA 232-296 ; HATPase_c 342-453
Cluster members and taxonomy
Visualization

Representative gene: GCF_000291155#II3_RS21925

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 218 · GCF_000399245
AssemblyBaci_cere_MC118_V1 · Scaffoldhaploid
Genome composition5 608 415 bp · 35,0% GCBacillus cereus MC118
Signal transduction countsGenes 116 · HK 64 · RR 52CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key