Gene detail

IIC_RS21260

Histidine kinase, Classic

Bacillus cereus VD021 · GCF_000399145

ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000399145#IIC_RS21260Stable P2CS identifier used across views.
GenomeGCF_000399145Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1000838Run 6 · 43 sequences · id 100% · cov 80% · representative
External referencesWP_002143958.1 · A0A0A0WUT8 · MIST4 IIC_RS21260RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage347 / 611 aa (56.8%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
HAMP: 188-257 aa (70 aa)1PAS_9: 277-373 aa (97 aa)2HisKA: 380-446 aa (67 aa)3HATPase_c: 492-604 aa (113 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
188-257 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:188:1.15e-16:257:70:69
2 PAS_9#2
277-373 aa · 97 aa · 15.9% of protein
Raw tokenPAS_9:277:0.00000000549:373:102:102
3 HisKA#3
380-446 aa · 67 aa · 11.0% of protein
Raw tokenHisKA:380:3.19e-18:446:67:64
4 HATPase_c#4
492-604 aa · 113 aa · 18.5% of protein
Raw tokenHATPase_c:492:1e-35:604:113:109
  • Raw architecture: HAMP:188:1.15e-16:257:70:69#PAS_9:277:0.00000000549:373:102:102#HisKA:380:3.19e-18:446:67:64#HATPase_c:492:1e-35:604:113:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000399145::NZ_KB976281.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span549337-551883Genomic interval covered by the local TCS group.
Identifiers
Old locus tagIIC_04136RefSeq proteinWP_002143958.1
Context group IDGCF_000399145::NZ_KB976281.1::G00053
Context members
IIC_RS21260IIC_RS21265
Partner locus tags
IIC_RS21260IIC_RS21265
Partner old locus tags
IIC_04136IIC_04137
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002143958.1Primary protein accession used for annex mappings.
UniProt accessionA0A0A0WUT8Primary UniProt accession resolved in the annex database.
UniProt IDA0A0A0WUT8_BACMYDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagIIC_RS21260Primary locus identifier stored in the genes table.
Old locus tagIIC_04136Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB976281.1Sequence record reported by the local genomic context database.
Genomic interval549 337-551 172 nt1 836 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span549 337-551 883 ntGCF_000399145::NZ_KB976281.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000399145::NZ_KB976281.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB976281.1All displayed genes belong to this local TCS context.
Neighborhood span549 337-551 883 nt2 547 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
549 337 nt551 883 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

IIC_RS21260GCF_000399145#IIC_RS21260
HKClassicCurrent focus

549 337-551 172 nt · Reverse (-)

Old locus IIC_04136RefSeq WP_002143958.1
IIC_RS21265GCF_000399145#IIC_RS21265
RROmpR

551 176-551 883 nt · Reverse (-)

Old locus IIC_04137RefSeq WP_000971867.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1000838Run 6 · HK · 43 sequences
Representative sequenceGCF_000399145#IIC_RS21260The current gene is the representative for this cluster.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1000838

Simplified PFAM architecture for HKOC_1000838

PFAM domain coverage: 374 / 611 aa (61.2%)

1 aa611 aa
Cache_WalK: 78-172 aaCache_WalKHAMP: 205-257 aaHAMPPAS: 269-317 aaPASHisKA: 381-446 aaHisKAHATPase_c: 493-603 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[78-172] | HAMP[205-257] | PAS[269-317] | HisKA[381-446] | HATPase_c[493-603]
  • Domain count: 5
  • Matched identifier: HKOC_1000838
  • Positioned domains: Cache_WalK 78-172 ; HAMP 205-257 ; PAS 269-317 ; HisKA 381-446 ; HATPase_c 493-603
Cluster members and taxonomy
Visualization

Representative gene: GCF_000399145#IIC_RS21260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 224 · GCF_000399145
AssemblyBaci_cere_VD021_V1 · Scaffoldhaploid
Genome composition6 097 836 bp · 35,0% GCBacillus cereus VD021
Signal transduction countsGenes 121 · HK 65 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key